Detailed information of TA system TA035797

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 1265513..1266180
• Replicon: chromosome
• Accession: NZ_AP022494
• Organism: Citrobacter portucalensis strain STN0717-36

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: JLF47_RS05970
• Protein ID: WP_200922842.1
• Coordinates: 1265513..1265842 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: JLF47_RS05975
• Protein ID: WP_087934336.1
• Coordinates: 1265863..1266180 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JLF47_RS05950	1260911..1261147	+	237	WP_200922844.1	hypothetical protein	-
JLF47_RS05955	1261176..1261613	+	438	WP_200932052.1	hypothetical protein	-
JLF47_RS05960	1261803..1263824	-	2022	WP_154023424.1	hypothetical protein	-
JLF47_RS05965	1263909..1265141	-	1233	WP_154023425.1	integrase arm-type DNA-binding domain-containing protein	-
JLF47_RS05970	1265513..1265842	-	330	WP_200922842.1	TA system toxin CbtA family protein	Toxin
JLF47_RS05975	1265863..1266180	-	318	WP_087934336.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
JLF47_RS05980	1266198..1266419	-	222	WP_200922841.1	DUF987 domain-containing protein	-
JLF47_RS05985	1266428..1266910	-	483	WP_200922840.1	DNA repair protein RadC	-
JLF47_RS05990	1266919..1267368	-	450	WP_200922839.1	antirestriction protein	-
JLF47_RS05995	1267468..1267707	-	240	WP_087934338.1	DUF905 domain-containing protein	-
JLF47_RS06000	1267784..1268251	-	468	WP_200922838.1	hypothetical protein	-
JLF47_RS06005	1268275..1268715	-	441	WP_097344773.1	hypothetical protein	-
JLF47_RS06010	1268715..1268951	-	237	WP_200922837.1	hypothetical protein	-
JLF47_RS06015	1268992..1269693	-	702	WP_200922836.1	WYL domain-containing protein	-
JLF47_RS06020	1269910..1270731	-	822	WP_200922835.1	DUF945 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1255226..1286613	31387

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-108)

Antitoxin

• Antitoxin CbeA (5-104)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12369.23 Da
• Isoelectric Point: 7.1987

>T35797 WP_200922842.1 NZ_AP022494:c1265842-1265513 [Citrobacter portucalensis]
MNTLPATTPQAAKLYLSPVSVWQMLLTYLLEQHYGLTLNDTPFSDETVIQEHIDAGVSLSDAVNFLVEKYGLIRIDRKGF
SWREQTPYISVVDILRARRSTGLLKTNVK

Nucleotide

• Length: 330 bp

>T35797 NZ_AP022494:c1265842-1265513 [Citrobacter portucalensis]
ATGAATACTCTACCTGCAACAACTCCGCAGGCGGCGAAGCTATATCTGTCGCCCGTGTCTGTCTGGCAAATGTTACTGAC
ATACCTGCTGGAACAGCACTATGGCCTGACCCTGAACGACACACCATTCAGTGATGAAACCGTAATACAGGAACACATTG
ATGCTGGAGTATCGCTCAGCGATGCGGTGAACTTTCTGGTAGAAAAATACGGGCTTATCCGTATCGACCGAAAGGGATTT
TCGTGGCGAGAACAAACCCCGTATATTTCCGTAGTGGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11770.30 Da
• Isoelectric Point: 6.4639

>AT35797 WP_087934336.1 NZ_AP022494:c1266180-1265863 [Citrobacter portucalensis]
MSNTTWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECPKLDVVFPDFISQIESMLTTGELNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIVVYSTQR

Nucleotide

• Length: 318 bp

>AT35797 NZ_AP022494:c1266180-1265863 [Citrobacter portucalensis]
ATGAGCAACACCACATGGGGCCTGCAGCGGGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAG
ATTTTATCAGCCAGATAGAGTCGATGTTGACCACTGGTGAACTGAATCCCCGTCATGCCCACTGCGTCACCCTGTACCAC
AACGGTTTCACCTGCGAAGCCGATACCCTTGGCAGTTGCGGCTACGTATACATCGTCGTCTATTCCACTCAACGCTGA