Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4699077..4699663 Replicon chromosome
Accession NZ_AP022473
Organism Pseudomonas monteilii strain STW0522-72

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JLF49_RS22260 Protein ID WP_082426425.1
Coordinates 4699370..4699663 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag JLF49_RS22255 Protein ID WP_182408666.1
Coordinates 4699077..4699373 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF49_RS22235 4696045..4696986 - 942 WP_200928792.1 FecR domain-containing protein -
JLF49_RS22240 4696986..4697492 - 507 WP_060499947.1 sigma-70 family RNA polymerase sigma factor -
JLF49_RS22245 4697788..4698435 + 648 WP_060499948.1 hypothetical protein -
JLF49_RS22250 4698587..4699075 + 489 WP_104833975.1 GNAT family N-acetyltransferase -
JLF49_RS22255 4699077..4699373 - 297 WP_182408666.1 putative addiction module antidote protein Antitoxin
JLF49_RS22260 4699370..4699663 - 294 WP_082426425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JLF49_RS22265 4699885..4700772 + 888 WP_060499951.1 effector protein -
JLF49_RS22270 4700769..4701536 - 768 WP_060499952.1 phosphonate ABC transporter, permease protein PhnE -
JLF49_RS22275 4701533..4702360 - 828 WP_060499953.1 ABC transporter permease subunit -
JLF49_RS22280 4702354..4703163 - 810 WP_182408667.1 ATP-binding cassette domain-containing protein -
JLF49_RS22285 4703160..4704014 - 855 WP_060499955.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10847.80 Da        Isoelectric Point: 10.5184

>T35708 WP_082426425.1 NZ_AP022473:c4699663-4699370 [Pseudomonas monteilii]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI

Download         Length: 294 bp

>T35708 NZ_AP022473:c4699663-4699370 [Pseudomonas monteilii]
ATGTATCTTGTTGAACAGACGGAGAGCTTTGCAGTTTGGCTATCCAGCTTGAGGGATTTGAAAGCCAAGCTTGCGATAGG
TCGCAGGCTGGAGCGAGTTGCGATAGGCAACCTTGGTGACTTCAAGTGGCTTGGAGGCGGGCTAGGTGAGCTTCGCATCG
ACGTAGGTGCAGGCTATCGCGTCTATTTCACGCAAAAGGGGCACAGATTGGTTCTGCTGCTGGTTGGCGGCGACAAGTCC
ACTCAAGTCGCCGATATTCTCAAATCAAGAAAGCTGCTGAAGGAGATGATATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10617.30 Da        Isoelectric Point: 6.2205

>AT35708 WP_182408666.1 NZ_AP022473:c4699373-4699077 [Pseudomonas monteilii]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIAMESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR

Download         Length: 297 bp

>AT35708 NZ_AP022473:c4699373-4699077 [Pseudomonas monteilii]
ATGAGCGAAAAACTGATTCCGTTTGATATGGCAGCTTTGTTGAGTAGCGATGAGGCCATCAGTGAGTACCTTAGCCAGGT
GCTATCAGATGGCGATACCGAAGAGATCATTCGAGCGCTCGGCCATATCGCGCGTGCACGAGGCATGACACACATAGCCA
TGGAGAGTGGTTTGGGCAGAGAAAGCCTCTACAAGGCGCTCAGCCCAGGCGCAAAGCCTCGTTTTGACACTGTGTTGAAG
GTCATTCGAGCCTTGGGGGTAGACCTTCTCGTGCAGCCCCATGCGGTAGCCCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References