Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 270713..271320 Replicon chromosome
Accession NZ_AP022473
Organism Pseudomonas monteilii strain STW0522-72

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag JLF49_RS01180 Protein ID WP_200928952.1
Coordinates 270713..271054 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A923H1P8
Locus tag JLF49_RS01185 Protein ID WP_025754068.1
Coordinates 271072..271320 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF49_RS01165 266146..267513 - 1368 WP_164524045.1 HAMP domain-containing protein -
JLF49_RS01170 267515..268237 - 723 WP_060501217.1 response regulator -
JLF49_RS01175 268378..270675 + 2298 WP_104833620.1 TonB-dependent siderophore receptor -
JLF49_RS01180 270713..271054 - 342 WP_200928952.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JLF49_RS01185 271072..271320 - 249 WP_025754068.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JLF49_RS01190 272043..273218 - 1176 WP_200928953.1 integrase -
JLF49_RS01195 273529..273762 - 234 WP_200928954.1 hypothetical protein -
JLF49_RS01200 273755..274207 - 453 WP_200928955.1 hypothetical protein -
JLF49_RS01205 274197..274400 - 204 WP_200928956.1 hypothetical protein -
JLF49_RS01210 274393..274941 - 549 WP_200928957.1 hypothetical protein -
JLF49_RS01215 274938..275213 - 276 WP_200928958.1 hypothetical protein -
JLF49_RS01220 275286..275453 - 168 WP_200928959.1 hypothetical protein -
JLF49_RS01225 275479..275793 - 315 WP_200928960.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-98)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12536.37 Da        Isoelectric Point: 6.3199

>T35706 WP_200928952.1 NZ_AP022473:c271054-270713 [Pseudomonas monteilii]
MPTIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNVDGYRVFYEV
IETDNAIAVGLVLRQKQSVEQALIRYCLIYPLP

Download         Length: 342 bp

>T35706 NZ_AP022473:c271054-270713 [Pseudomonas monteilii]
ATGCCGACCATACGCTTCACCCATTCCGCCTCTCAGAGCATCGAAGATCAAGTCCACCATCTGGCCGTCTATCACGGTAC
CGCAGCGGCACTTGAGAAAATCACCACACTGGTCGACACCATTGAGCACCGGCTGGCTGCCGCGCCCGTGGGTTACCCGG
TCAGCCCACAAGCGAGCGGGCTGGGTGTCATGCAGTATCGTGAGCTGAATGTCGACGGGTACAGGGTGTTCTACGAAGTG
ATCGAAACCGACAATGCCATTGCCGTGGGGTTGGTTCTCAGGCAAAAGCAGAGTGTTGAACAGGCATTGATTCGGTATTG
CCTGATTTACCCATTACCTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9307.61 Da        Isoelectric Point: 6.4706

>AT35706 WP_025754068.1 NZ_AP022473:c271320-271072 [Pseudomonas monteilii]
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKTRLLKKFS
EE

Download         Length: 249 bp

>AT35706 NZ_AP022473:c271320-271072 [Pseudomonas monteilii]
ATGCGAGTAGAAACGATCAGCTACCTGAAACGCCATGCTGCTGACCTGGACCTGGAAGAACCCATGGTCGTGACACAGAA
CGGTGTGCCTGCCTATGTGGTCGAGTCCTACGCGGATCGCAAGCAACGGGATGAAGCCATAGCCTTGGTGAAACTGCTCG
CCATCGGTTCCCGTGAGTATGCTCAGGGCAAACACAGCTCGGCCGAAGACCTCAAGACTCGCCTTCTCAAGAAATTTTCT
GAGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References