Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-KacA/DUF1778(antitoxin)
Location 1554631..1555419 Replicon chromosome
Accession NZ_AP022465
Organism Enterobacter roggenkampii strain STW0522-66

Toxin (Protein)


Gene name ataT Uniprot ID A0A156ENK5
Locus tag JLF42_RS07310 Protein ID WP_032663845.1
Coordinates 1554631..1555143 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name KacA Uniprot ID W7PG43
Locus tag JLF42_RS07315 Protein ID WP_008499829.1
Coordinates 1555150..1555419 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF42_RS07280 1550205..1550894 + 690 WP_055322185.1 pyrimidine utilization protein B -
JLF42_RS07285 1550906..1551292 + 387 WP_055322186.1 pyrimidine utilization protein C -
JLF42_RS07290 1551300..1552100 + 801 WP_023292821.1 pyrimidine utilization protein D -
JLF42_RS07295 1552110..1552700 + 591 WP_023327079.1 malonic semialdehyde reductase -
JLF42_RS07300 1552710..1553204 + 495 WP_023292823.1 pyrimidine utilization flavin reductase protein F -
JLF42_RS07305 1553226..1554548 + 1323 WP_008499826.1 pyrimidine utilization transport protein G -
JLF42_RS07310 1554631..1555143 - 513 WP_032663845.1 GNAT family N-acetyltransferase Toxin
JLF42_RS07315 1555150..1555419 - 270 WP_008499829.1 DUF1778 domain-containing protein Antitoxin
JLF42_RS07320 1555481..1556398 - 918 WP_023292825.1 DMT family transporter -
JLF42_RS07325 1556518..1556688 - 171 WP_013097201.1 general stress protein -
JLF42_RS07330 1557080..1557676 + 597 WP_008499831.1 NAD(P)H:quinone oxidoreductase -
JLF42_RS07335 1557697..1557924 + 228 WP_008499832.1 YccJ family protein -
JLF42_RS07340 1557960..1559201 - 1242 WP_008499833.1 bifunctional glucose-1-phosphatase/inositol phosphatase -
JLF42_RS07345 1559354..1559797 + 444 WP_008499834.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 19328.10 Da        Isoelectric Point: 7.9331

>T35693 WP_032663845.1 NZ_AP022465:c1555143-1554631 [Enterobacter roggenkampii]
VDNLTIEMFSEGKDYDFRDFDCGEPSLNVFLTEHLVRQHNGRILRGYLLKDRDGPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAIHKDLQGLEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNDQAKQFYLKQGFIPLTGENSHSLF
FPTKSIERLF

Download         Length: 513 bp

>T35693 NZ_AP022465:c1555143-1554631 [Enterobacter roggenkampii]
GTGGACAATCTCACGATCGAAATGTTTTCAGAGGGAAAAGACTATGATTTCAGGGACTTCGATTGTGGTGAACCCTCGCT
AAATGTCTTCCTCACAGAACATCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGGCTATTTGCTTAAAGATCGCGATG
GTCCGCGAGTCCTGGGCTATTACACGTTGTCTGGTAGTTGCTTTGAAAAAGCGATGCTGCCTTCTAAGACTCAGCAGCGT
CGGATCCCTTATAGCAACGTACCGAGCGTAACGCTGGGACGTCTGGCGATACATAAAGACTTACAGGGGCTGGAGTGGGG
AACGACGCTCGTCACGCATGCCATGCGGGTTGTCTATCTGGCATCGCAGGCGGTGGGCGTACACGGAATATTTGTTGATG
CACTCAACGACCAGGCAAAACAATTTTATCTGAAGCAGGGCTTTATTCCGCTGACGGGTGAAAACAGCCATTCTCTTTTC
TTTCCTACAAAATCTATCGAACGACTGTTTTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10262.72 Da        Isoelectric Point: 5.8836

>AT35693 WP_008499829.1 NZ_AP022465:c1555419-1555150 [Enterobacter roggenkampii]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPNERLKR
AAKRLRNME

Download         Length: 270 bp

>AT35693 NZ_AP022465:c1555419-1555150 [Enterobacter roggenkampii]
ATGCCAGCACTGAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACGAATCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGGGCAGCGGAAGTCATCGAGCAGCACCGCCGTC
TCGTATTAAACGAAGCATCCTGGAATGCGGTGATGGATGCCATCGACAATCCACCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A156ENK5

Antitoxin

Source ID Structure
AlphaFold DB W7PG43

References