Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 240530..241431 Replicon plasmid pSTW0522-60-1
Accession NZ_AP022447
Organism Enterobacter kobei strain STW0522-60

Toxin (Protein)


Gene name - Uniprot ID S1EZ83
Locus tag JLF31_RS25770 Protein ID WP_008786589.1
Coordinates 240530..240988 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JLF31_RS25775 Protein ID WP_008786588.1
Coordinates 240985..241431 (-) Length 149 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF31_RS25725 236256..236498 + 243 WP_007372291.1 hypothetical protein -
JLF31_RS25730 236509..236907 + 399 WP_007372292.1 hypothetical protein -
JLF31_RS25735 236991..237317 + 327 WP_007372293.1 hypothetical protein -
JLF31_RS25740 237680..238018 - 339 WP_007372294.1 hypothetical protein -
JLF31_RS25745 238256..238699 + 444 WP_007372295.1 hypothetical protein -
JLF31_RS25750 238818..239159 + 342 WP_007372296.1 hypothetical protein -
JLF31_RS25755 239318..239872 + 555 WP_007372297.1 hypothetical protein -
JLF31_RS25760 239922..240188 + 267 WP_007372298.1 hypothetical protein -
JLF31_RS25765 240256..240486 - 231 WP_007372299.1 hypothetical protein -
JLF31_RS25770 240530..240988 - 459 WP_008786589.1 RES family NAD+ phosphorylase Toxin
JLF31_RS25775 240985..241431 - 447 WP_008786588.1 DUF2384 domain-containing protein Antitoxin
JLF31_RS25780 241580..241897 + 318 WP_016241555.1 hypothetical protein -
JLF31_RS25785 241939..242781 + 843 WP_007372303.1 hypothetical protein -
JLF31_RS25790 242753..243031 + 279 WP_007372304.1 hypothetical protein -
JLF31_RS25795 243091..243534 + 444 WP_007372305.1 hypothetical protein -
JLF31_RS25800 243821..243985 + 165 WP_007372306.1 hypothetical protein -
JLF31_RS25805 244553..245395 + 843 WP_007372307.1 HNH endonuclease -
JLF31_RS25810 245817..246068 + 252 WP_024196080.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..278483 278483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 153 a.a.        Molecular weight: 22536.04 Da        Isoelectric Point: 5.5500

>T35669 WP_008786589.1 NZ_AP022447:c240988-240530 [Enterobacter kobei]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 459 bp

>T35669 NZ_AP022447:c240988-240530 [Enterobacter kobei]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 21947.33 Da        Isoelectric Point: 5.5500

>AT35669 WP_008786588.1 NZ_AP022447:c241431-240985 [Enterobacter kobei]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 447 bp

>AT35669 NZ_AP022447:c241431-240985 [Enterobacter kobei]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB S1EZ83


Antitoxin

Source ID Structure

References