Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1958070..1958217 Replicon chromosome
Accession NZ_AP022412
Organism Klebsiella quasipneumoniae strain STW0522-39

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1958111..1958213 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1958070..1958217 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF46_RS09580 1954168..1954827 - 660 WP_004203387.1 exodeoxyribonuclease X -
JLF46_RS09585 1954906..1955136 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JLF46_RS09590 1955243..1956331 + 1089 WP_200927913.1 IS481 family transposase -
JLF46_RS09595 1956350..1956724 + 375 WP_194417786.1 CopC domain-containing protein YobA -
JLF46_RS09600 1956728..1957597 + 870 WP_004203385.1 copper homeostasis membrane protein CopD -
JLF46_RS09605 1957614..1957952 + 339 WP_002911404.1 YebY family protein -
- 1958070..1958217 - 148 - - Antitoxin
- 1958111..1958213 + 103 - - Toxin
JLF46_RS09610 1958601..1958744 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
JLF46_RS09615 1958848..1959816 - 969 WP_004203383.1 VirK/YbjX family protein -
JLF46_RS09620 1959973..1960626 + 654 WP_099441356.1 protein-serine/threonine phosphatase -
JLF46_RS09625 1960623..1960814 - 192 WP_002911395.1 YebW family protein -
JLF46_RS09630 1960912..1961151 - 240 WP_002911393.1 YebV family protein -
JLF46_RS09635 1961268..1962701 - 1434 WP_200927914.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1952137..1965463 13326
- flank IS/Tn - - 1955243..1956331 1088


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T35622 NZ_AP022412:1958111-1958213 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT35622 NZ_AP022412:c1958217-1958070 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References