Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2064633..2064904 Replicon chromosome
Accession NZ_AP022409
Organism Escherichia coli strain STW0522-31

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2064763..2064866 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2064633..2064904 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLE49_RS09835 2061188..2061850 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLE49_RS09840 2061874..2062530 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JLE49_RS09845 2062632..2062862 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLE49_RS09850 2063001..2063375 + 375 WP_000204700.1 CopC domain-containing protein YobA -
JLE49_RS09855 2063379..2064251 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
JLE49_RS09860 2064264..2064605 + 342 WP_000976472.1 YebY family protein -
- 2064633..2064904 - 272 - - Antitoxin
- 2064763..2064866 + 104 - - Toxin
JLE49_RS09865 2065001..2065657 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
JLE49_RS09870 2065658..2065849 - 192 WP_001296140.1 YebW family protein -
JLE49_RS09875 2065954..2066190 - 237 WP_001295499.1 DUF1480 family protein -
JLE49_RS09880 2066308..2067747 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T35599 NZ_AP022409:2064763-2064866 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT35599 NZ_AP022409:c2064904-2064633 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References