35576

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 942411..943065 Replicon chromosome
Accession NZ_AP022399
Organism Citrobacter portucalensis strain STW0522-30

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JLF43_RS04580 Protein ID WP_200922871.1
Coordinates 942658..943065 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JLF43_RS04575 Protein ID WP_003825514.1
Coordinates 942411..942677 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF43_RS04550 937566..938999 - 1434 WP_149334913.1 6-phospho-beta-glucosidase BglA -
JLF43_RS04555 939120..939848 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
JLF43_RS04560 939901..940212 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
JLF43_RS04565 940376..941038 + 663 WP_063940912.1 hemolysin III family protein -
JLF43_RS04570 941170..942153 - 984 WP_200921215.1 tRNA-modifying protein YgfZ -
JLF43_RS04575 942411..942677 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
JLF43_RS04580 942658..943065 + 408 WP_200922871.1 protein YgfX Toxin
JLF43_RS04585 943167..943688 - 522 WP_003825517.1 flavodoxin FldB -
JLF43_RS04590 943802..944698 + 897 WP_063940914.1 site-specific tyrosine recombinase XerD -
JLF43_RS04595 944722..945435 + 714 WP_200927049.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JLF43_RS04600 945441..947174 + 1734 WP_063940915.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15852.74 Da        Isoelectric Point: 11.5783

>T35576 WP_200922871.1 NZ_AP022399:942658-943065 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRRQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T35576 NZ_AP022399:942658-943065 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
GTTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCAGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT35576 WP_003825514.1 NZ_AP022399:942411-942677 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT35576 NZ_AP022399:942411-942677 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References