Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3958257..3958911 Replicon chromosome
Accession NZ_AP022394
Organism Citrobacter portucalensis strain STW0522-27

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JLF33_RS19005 Protein ID WP_200922871.1
Coordinates 3958257..3958664 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JLF33_RS19010 Protein ID WP_003825514.1
Coordinates 3958645..3958911 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF33_RS18985 3954148..3955881 - 1734 WP_063940915.1 single-stranded-DNA-specific exonuclease RecJ -
JLF33_RS18990 3955887..3956600 - 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JLF33_RS18995 3956624..3957520 - 897 WP_063940914.1 site-specific tyrosine recombinase XerD -
JLF33_RS19000 3957634..3958155 + 522 WP_003825517.1 flavodoxin FldB -
JLF33_RS19005 3958257..3958664 - 408 WP_200922871.1 protein YgfX Toxin
JLF33_RS19010 3958645..3958911 - 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
JLF33_RS19015 3959169..3960152 + 984 WP_200921215.1 tRNA-modifying protein YgfZ -
JLF33_RS19020 3960284..3960946 - 663 WP_063940912.1 hemolysin III family protein -
JLF33_RS19025 3961110..3961421 - 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
JLF33_RS19030 3961474..3962202 + 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
JLF33_RS19035 3962323..3963756 + 1434 WP_149334913.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15852.74 Da        Isoelectric Point: 11.5783

>T35568 WP_200922871.1 NZ_AP022394:c3958664-3958257 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRRQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T35568 NZ_AP022394:c3958664-3958257 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
GTTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCAGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT35568 WP_003825514.1 NZ_AP022394:c3958911-3958645 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT35568 NZ_AP022394:c3958911-3958645 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References