Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1061303..1061869 Replicon chromosome
Accession NZ_AP022379
Organism Bifidobacterium longum subsp. longum strain JCM 7052

Toxin (Protein)


Gene name relE Uniprot ID W6EX94
Locus tag BLGA_RS04510 Protein ID WP_003831807.1
Coordinates 1061303..1061596 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID I3BGP0
Locus tag BLGA_RS04515 Protein ID WP_007056990.1
Coordinates 1061600..1061869 (-) Length 90 a.a.

Genomic Context

BLGA_RS04495BLGA_RS04500BLGA_RS04540BLGA_RS04475BLGA_RS04480BLGA_RS04485BLGA_RS04490BLGA_RS04505BLGA_RS04510BLGA_RS04515BLGA_RS04520BLGA_RS04525BLGA_RS04530BLGA_RS04535
Location: 1059998..1060177 (180 bp)
Type: Others
Protein ID: WP_007056286.1
Location: 1060174..1060758 (585 bp)
Type: Others
Protein ID: WP_007056278.1
Location: 1065425..1066120 (696 bp)
Type: Others
Protein ID: WP_119107335.1
Location: 1056544..1056957 (414 bp)
Type: Others
Protein ID: Protein_864
Location: 1057072..1057836 (765 bp)
Type: Others
Protein ID: WP_012472066.1
Location: 1057833..1059356 (1524 bp)
Type: Others
Protein ID: WP_200764690.1
Location: 1059551..1059784 (234 bp)
Type: Others
Protein ID: Protein_867
Location: 1060961..1061245 (285 bp)
Type: Others
Protein ID: WP_007056282.1
Location: 1061303..1061596 (294 bp)
Type: Toxin
Protein ID: WP_003831807.1
Location: 1061600..1061869 (270 bp)
Type: Antitoxin
Protein ID: WP_007056990.1
Location: 1062054..1063223 (1170 bp)
Type: Others
Protein ID: WP_080824247.1
Location: 1063220..1063900 (681 bp)
Type: Others
Protein ID: WP_003829413.1
Location: 1063897..1064787 (891 bp)
Type: Others
Protein ID: WP_007056280.1
Location: 1064784..1065299 (516 bp)
Type: Others
Protein ID: WP_032685213.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BLGA_RS044751056544..1056957-414Protein_864moaA protein-
BLGA_RS044801057072..1057836-765WP_012472066.1IS21-like element ISBlo1 family helper ATPase IstB-
BLGA_RS044851057833..1059356-1524WP_200764690.1IS21 family transposase-
BLGA_RS044901059551..1059784-234Protein_867moaA protein-
BLGA_RS044951059998..1060177+180WP_007056286.1antitoxin VbhA family protein-
BLGA_RS045001060174..1060758+585WP_007056278.1Fic family protein-
BLGA_RS045051060961..1061245-285WP_007056282.1hypothetical protein-
BLGA_RS045101061303..1061596-294WP_003831807.1type II toxin-antitoxin system YafQ family toxinToxin
BLGA_RS045151061600..1061869-270WP_007056990.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
BLGA_RS045201062054..1063223-1170WP_080824247.1ABC transporter permease-
BLGA_RS045251063220..1063900-681WP_003829413.1ABC transporter ATP-binding protein-
BLGA_RS045301063897..1064787-891WP_007056280.1hypothetical protein-
BLGA_RS045351064784..1065299-516WP_032685213.1hypothetical protein-
BLGA_RS045401065425..1066120+696WP_119107335.1response regulator transcription factor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1039876..107617036294


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-87)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11218.98 Da        Isoelectric Point: 9.7881

>T35534 WP_003831807.1 NZ_AP022379:c1061596-1061303 [Bifidobacterium longum subsp. longum]
MLKPDYTAAFQRDIKKLKRKHTDLRPLKEVIRLVLEDTADSKEVLRRRHRAHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK

Download         Length: 294 bp

>T35534 NZ_AP022379:c1061596-1061303 [Bifidobacterium longum subsp. longum]
ATGCTCAAACCGGATTACACGGCGGCATTCCAGCGAGATATCAAGAAGCTCAAACGCAAGCACACTGATTTACGCCCGCT
GAAAGAAGTCATTCGTCTGGTTCTTGAGGACACGGCGGACTCCAAGGAAGTATTGAGGCGTAGGCATCGCGCCCACACAC
TTACCGGTGATTTAAACGGCGTACTGGAATGCCACATCGGCAATGCCGGCGACTGGCTACTTCTATGGATTCGCGATGAT
GGTACCGCCATGTTCATGCGAACCGGCAGCCATGACGAACTGTTGGGCAAATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9844.16 Da        Isoelectric Point: 4.5742

>AT35534 WP_007056990.1 NZ_AP022379:c1061869-1061600 [Bifidobacterium longum subsp. longum]
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVREKRIPLNLSYTIVPPETMEALDEAKNRLADGQPRFNSA
DEMFDSLGI

Download         Length: 270 bp

>AT35534 NZ_AP022379:c1061869-1061600 [Bifidobacterium longum subsp. longum]
GTGAGCATGGCATCCGTCACAGTCCGCGTGGATGCGGACACCAAGCAGAAAGCCGCAAACATAGCCGAGGATCTCGGTCT
GGACTTGTCTTCGGTCACCCGCGCCTTCTACAAGCAGATTGTCCGGGAGAAGCGCATTCCCCTAAACCTTTCCTATACGA
TCGTGCCGCCTGAAACCATGGAGGCCCTTGACGAGGCGAAGAACAGGCTCGCCGACGGCCAACCTCGCTTCAACAGTGCC
GATGAGATGTTCGATTCGTTGGGAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBW6EX94

Antitoxin

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Source
ID
Structure
AlphaFold DBI3BGP0

References