Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1148510..1149188 Replicon chromosome
Accession NZ_AP022378
Organism Citrobacter portucalensis strain IOMTU157

Toxin (Protein)


Gene name yeeV Uniprot ID A0A9K1QZI5
Locus tag IOMTU157_RS05540 Protein ID WP_032949840.1
Coordinates 1148510..1148833 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A9K1QZR3
Locus tag IOMTU157_RS05545 Protein ID WP_032642918.1
Coordinates 1148865..1149188 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOMTU157_RS05520 1143905..1144795 + 891 WP_149334934.1 myo-inosose-2 dehydratase -
IOMTU157_RS05525 1144805..1145623 + 819 WP_164562524.1 5-deoxy-glucuronate isomerase -
IOMTU157_RS05530 1145818..1146174 - 357 WP_003826111.1 hypothetical protein -
IOMTU157_RS05535 1146723..1147604 - 882 WP_063941013.1 hypothetical protein -
IOMTU157_RS05540 1148510..1148833 - 324 WP_032949840.1 TA system toxin CbtA family protein Toxin
IOMTU157_RS05545 1148865..1149188 - 324 WP_032642918.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
IOMTU157_RS05550 1149210..1149431 - 222 WP_032642916.1 DUF987 domain-containing protein -
IOMTU157_RS05555 1149440..1149910 - 471 WP_032642914.1 DNA repair protein RadC -
IOMTU157_RS05560 1149943..1150764 - 822 WP_032642912.1 DUF945 domain-containing protein -
IOMTU157_RS05565 1150985..1151425 - 441 WP_135695985.1 NirD/YgiW/YdeI family stress tolerance protein -
IOMTU157_RS05570 1151586..1152728 - 1143 WP_029602872.1 nickel/cobalt efflux protein RcnA -
IOMTU157_RS05575 1152741..1153010 - 270 WP_009653703.1 metal-sensing transcriptional repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12143.94 Da        Isoelectric Point: 6.0673

>T35519 WP_032949840.1 NZ_AP022378:c1148833-1148510 [Citrobacter portucalensis]
MQISSVPATVPVSSRLSPVMVWQQLLTYLLEHHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELARIDRKGF
TWREQPPFITATDILRAKKNIGLLPRS

Download         Length: 324 bp

>T35519 NZ_AP022378:c1148833-1148510 [Citrobacter portucalensis]
ATGCAAATTTCATCTGTACCGGCCACGGTGCCGGTTTCGTCACGCCTGTCGCCCGTAATGGTGTGGCAGCAGTTGTTAAC
GTATCTGCTGGAGCACCACTACGGCCTCACACTCAACGACACACCATTTCATGACGACACGGCCATTGAGGAGCATATCG
ATGCGGGGATAACGCTTGCCGATGCTGTTAATTTCCTGGTCGAAAAGTACGAACTGGCTCGTATCGACCGCAAGGGATTT
ACATGGCGAGAGCAACCCCCCTTCATTACTGCAACGGATATTCTGCGTGCCAAAAAGAACATCGGGCTGTTGCCCAGATC
TTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12082.82 Da        Isoelectric Point: 6.6250

>AT35519 WP_032642918.1 NZ_AP022378:c1149188-1148865 [Citrobacter portucalensis]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNEEEALRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLYHN
GLTCEADTLGSHGYVYIVIYPQAFATR

Download         Length: 324 bp

>AT35519 NZ_AP022378:c1149188-1148865 [Citrobacter portucalensis]
ATGCAAAATTCATGGGGACTGAAGCGCGACATCTCGCCGTGCTTCGGTGCAAGGCTTGTGCAGGAAGGCTGTCGCCTGCA
TTTTCTGGCGGACCGTGCAGGTATTAGTGGTACGTTTAACGAGGAGGAGGCACTGCGTCTGGATCAGGCATTTCCGCTAG
TGATGAAACAGCTTGAATTGATGCTGACAACCGGTGAACTAAATCCGCGCCATCAGCATTGCGTCACGTTGTATCATAAC
GGACTAACTTGTGAAGCTGACACTCTCGGCTCTCATGGCTATGTTTACATCGTTATTTATCCTCAGGCATTTGCAACCAG
GTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References