Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 856525..857179 Replicon chromosome
Accession NZ_AP022378
Organism Citrobacter portucalensis strain IOMTU157

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IOMTU157_RS04235 Protein ID WP_003825515.1
Coordinates 856772..857179 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IOMTU157_RS04230 Protein ID WP_003825514.1
Coordinates 856525..856791 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOMTU157_RS04205 851679..853112 - 1434 WP_164562491.1 6-phospho-beta-glucosidase BglA -
IOMTU157_RS04210 853234..853962 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
IOMTU157_RS04215 854015..854326 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
IOMTU157_RS04220 854490..855152 + 663 WP_063940912.1 hemolysin III family protein -
IOMTU157_RS04225 855284..856267 - 984 WP_164562492.1 tRNA-modifying protein YgfZ -
IOMTU157_RS04230 856525..856791 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
IOMTU157_RS04235 856772..857179 + 408 WP_003825515.1 protein YgfX Toxin
IOMTU157_RS04240 857281..857802 - 522 WP_003825517.1 flavodoxin FldB -
IOMTU157_RS04245 857916..858812 + 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
IOMTU157_RS04250 858836..859549 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
IOMTU157_RS04255 859555..861288 + 1734 WP_164562493.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T35518 WP_003825515.1 NZ_AP022378:856772-857179 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T35518 NZ_AP022378:856772-857179 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTGTTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT35518 WP_003825514.1 NZ_AP022378:856525-856791 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT35518 NZ_AP022378:856525-856791 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGACT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References