Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3604350..3604888 Replicon chromosome
Accession NZ_AP022371
Organism Providencia rettgeri strain BML2496

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G7Y72_RS16845 Protein ID WP_096864800.1
Coordinates 3604350..3604640 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G7Y72_RS16850 Protein ID WP_096864799.1
Coordinates 3604637..3604888 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7Y72_RS16805 3599811..3600203 + 393 WP_096864805.1 hypothetical protein -
G7Y72_RS16810 3600221..3600421 - 201 Protein_3285 MFS transporter -
G7Y72_RS16815 3600501..3600632 - 132 Protein_3286 AraC family transcriptional regulator -
G7Y72_RS16820 3600729..3601910 - 1182 WP_096864804.1 cyanate transporter -
G7Y72_RS16825 3601907..3602374 - 468 WP_096864803.1 nucleoside deaminase -
G7Y72_RS16830 3602374..3603060 - 687 WP_004905375.1 ankyrin repeat domain-containing protein -
G7Y72_RS16835 3603127..3604002 + 876 WP_096864802.1 LysR family transcriptional regulator -
G7Y72_RS16840 3603999..3604355 + 357 WP_197739765.1 DUF4440 domain-containing protein -
G7Y72_RS16845 3604350..3604640 - 291 WP_096864800.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G7Y72_RS16850 3604637..3604888 - 252 WP_096864799.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G7Y72_RS16855 3605064..3606140 - 1077 WP_094962157.1 class II fructose-bisphosphate aldolase -
G7Y72_RS16860 3606200..3607363 - 1164 WP_004905385.1 phosphoglycerate kinase -
G7Y72_RS16865 3607456..3608475 - 1020 WP_004905387.1 erythrose-4-phosphate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11096.18 Da        Isoelectric Point: 10.7261

>T35483 WP_096864800.1 NZ_AP022371:c3604640-3604350 [Providencia rettgeri]
MTGFYKVKFRDDAAKEWKKLGATVQKQFAKKLKLLIENPHIPSARLSGLQNCYKIKLKASGYRLVYEVVDNQLIIIVVTV
GKRNRNEVYDVAKKRL

Download         Length: 291 bp

>T35483 NZ_AP022371:c3604640-3604350 [Providencia rettgeri]
ATGACAGGGTTCTATAAAGTTAAGTTTAGGGACGATGCAGCAAAAGAGTGGAAAAAGCTTGGTGCAACAGTACAGAAGCA
ATTCGCCAAGAAACTAAAATTACTGATTGAGAATCCCCATATACCTTCCGCAAGGCTCAGTGGGCTGCAAAATTGTTATA
AGATTAAGCTGAAAGCATCGGGTTATCGCTTAGTATACGAAGTTGTTGATAATCAGCTTATTATAATTGTGGTCACTGTG
GGGAAAAGGAATCGTAACGAGGTTTATGATGTTGCAAAAAAGCGGCTATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9307.70 Da        Isoelectric Point: 4.2558

>AT35483 WP_096864799.1 NZ_AP022371:c3604888-3604637 [Providencia rettgeri]
MPQVILSNVTASISELKKNPMATVDSGEGFPVAILNRNKPAFYCVPAEIYENLLEQIEDKELIEIVNARKNQKLVDVDLD
SYL

Download         Length: 252 bp

>AT35483 NZ_AP022371:c3604888-3604637 [Providencia rettgeri]
ATGCCTCAAGTTATTTTAAGTAATGTTACGGCGAGCATCAGTGAGCTAAAGAAAAACCCTATGGCGACAGTGGATTCTGG
TGAGGGGTTCCCTGTGGCTATTCTGAATAGAAATAAGCCTGCATTTTATTGTGTTCCAGCTGAAATATATGAAAATTTAT
TGGAACAAATTGAAGACAAAGAACTTATTGAAATTGTTAACGCAAGGAAAAACCAGAAGCTTGTAGATGTGGATTTGGAT
AGCTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References