Detailed information of TA system TA035480

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2090867..2091783
• Replicon: chromosome
• Accession: NZ_AP022371
• Organism: Providencia rettgeri strain BML2496

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: G7Y72_RS09520
• Protein ID: WP_096863732.1
• Coordinates: 2091325..2091783 (+)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: G7Y72_RS09515
• Protein ID: WP_096863734.1
• Coordinates: 2090867..2091328 (+)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G7Y72_RS09485	2086537..2087151	+	615	WP_164561034.1	LysE family translocator	-
G7Y72_RS09490	2087175..2087648	-	474	WP_096863737.1	NUDIX domain-containing protein	-
G7Y72_RS09495	2088000..2088641	-	642	WP_096863735.1	leucine efflux protein LeuE	-
G7Y72_RS09500	2089112..2089812	+	701	Protein_1849	AzlC family ABC transporter permease	-
G7Y72_RS09505	2089809..2090123	+	315	WP_004254498.1	AzlD domain-containing protein	-
G7Y72_RS09510	2090311..2090778	+	468	WP_094960596.1	DUF1456 family protein	-
G7Y72_RS09515	2090867..2091328	+	462	WP_096863734.1	DUF2384 domain-containing protein	Antitoxin
G7Y72_RS09520	2091325..2091783	+	459	WP_096863732.1	RES domain-containing protein	Toxin
G7Y72_RS09525	2091784..2092674	-	891	WP_096863730.1	LysR family transcriptional regulator	-
G7Y72_RS09530	2092720..2093679	-	960	WP_096863728.1	acetyl-CoA carboxylase carboxyl transferase subunit alpha	-
G7Y72_RS09535	2093785..2094207	-	423	WP_096863726.1	helix-turn-helix domain-containing protein	-
G7Y72_RS09540	2094238..2094801	-	564	WP_096863725.1	GNAT family N-acetyltransferase	-
G7Y72_RS09545	2094782..2096248	-	1467	WP_036957754.1	AMP nucleosidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-146)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (38-95)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17148.67 Da
• Isoelectric Point: 6.4824

>T35480 WP_096863732.1 NZ_AP022371:2091325-2091783 [Providencia rettgeri]
MILYRLVKSNFAHDAWSGQGAMLYGGRWNHKGTPAVYTSTSISLATLEILVHINQDRLLNQFSLLSIDINDKYVMKLSLD
HLPTDWQQDPAPTSTMDIGTIWLNNQDSLALLIPSCIVPYEYNAIINPLHPQFQKALHTVKSLDFSVDPRLA

Nucleotide

• Length: 459 bp

>T35480 NZ_AP022371:2091325-2091783 [Providencia rettgeri]
ATGATTTTATATCGATTGGTTAAATCCAATTTTGCGCATGATGCATGGTCAGGCCAAGGAGCCATGCTCTACGGCGGACG
TTGGAATCATAAAGGGACTCCTGCTGTTTATACTTCAACGAGTATTTCATTAGCAACCCTTGAAATACTCGTTCACATCA
ATCAAGACAGACTATTGAACCAGTTCAGCTTACTATCCATAGATATCAATGATAAGTATGTGATGAAATTGTCGTTAGAC
CACCTTCCGACAGATTGGCAACAAGACCCCGCACCAACCTCCACCATGGATATTGGCACTATATGGCTTAATAACCAAGA
TAGTCTAGCATTATTAATTCCCTCTTGTATTGTTCCCTATGAATACAACGCAATTATTAACCCGTTACATCCGCAATTTC
AAAAAGCTTTACATACCGTTAAATCACTAGATTTTAGTGTTGACCCGCGCTTAGCATAA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 17060.54 Da
• Isoelectric Point: 9.9140

>AT35480 WP_096863734.1 NZ_AP022371:2090867-2091328 [Providencia rettgeri]
MRNYIPTAPLQPTASSFKPLWRHVGLPAERGIELTHFLRQGLSVSVLDNIQEWSGMSKTELLRISGINERNIARRKNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKHAASDWLNHPVKGLGHLRPIELIATESGAIEVIDLIGRIEHGVFS

Nucleotide

• Length: 462 bp

>AT35480 NZ_AP022371:2090867-2091328 [Providencia rettgeri]
ATGAGAAACTATATCCCCACAGCCCCACTTCAACCGACTGCTTCATCCTTTAAACCACTGTGGCGCCATGTAGGGTTACC
CGCAGAACGTGGTATTGAGTTAACTCATTTCTTGCGTCAAGGCCTATCTGTCTCTGTCTTAGACAATATCCAAGAATGGT
CAGGAATGAGCAAAACTGAATTATTGCGAATATCCGGCATTAATGAGCGCAATATTGCGCGACGTAAAAATGCTGGCCAG
CCCCTTAATGCTGATGAAAGTGAGAGAATTGCTCGTCTAGTGCGGGTATTCGATGCTGCGGTGCGTTTATTTAATGGAGA
TAAGCACGCGGCAAGTGATTGGCTTAACCACCCAGTTAAAGGGTTAGGACATTTACGCCCTATTGAGCTTATTGCGACAG
AAAGCGGAGCCATTGAAGTGATTGATTTGATTGGCCGTATTGAACATGGCGTATTCTCATGA