Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2754528..2754796 Replicon chromosome
Accession NZ_AP022351
Organism Escherichia coli strain E138

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2754566..2754668 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2754528..2754796 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GR930_RS13505 2751686..2753125 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GR930_RS13510 2753242..2753478 + 237 WP_001295499.1 DUF1480 family protein -
GR930_RS13515 2753583..2753774 + 192 WP_001296140.1 YebW family protein -
GR930_RS13520 2753775..2754431 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 2754528..2754796 + 269 - - Antitoxin
- 2754566..2754668 - 103 - - Toxin
GR930_RS13525 2754826..2755167 - 342 WP_000976472.1 YebY family protein -
GR930_RS13530 2755180..2756052 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
GR930_RS13535 2756056..2756430 - 375 WP_000168747.1 CopC domain-containing protein YobA -
GR930_RS13540 2756569..2756799 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GR930_RS13545 2756901..2757557 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
GR930_RS13550 2757581..2758243 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T35426 NZ_AP022351:c2754668-2754566 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT35426 NZ_AP022351:2754528-2754796 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References