Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/AbrB(antitoxin)
Location 1829140..1829695 Replicon chromosome
Accession NZ_AP022347
Organism Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag ICHIJ1_RS09195 Protein ID WP_162050318.1
Coordinates 1829360..1829695 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag ICHIJ1_RS09190 Protein ID WP_162050317.1
Coordinates 1829140..1829370 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIJ1_RS09165 1825739..1826884 + 1146 WP_162050312.1 molecular chaperone DnaJ -
ICHIJ1_RS09170 1826998..1827549 - 552 WP_162050313.1 hypothetical protein -
ICHIJ1_RS09175 1827880..1828209 - 330 WP_162050314.1 hypothetical protein -
ICHIJ1_RS09180 1828215..1828694 - 480 WP_162050315.1 hypothetical protein -
ICHIJ1_RS09185 1828820..1829056 - 237 WP_162050316.1 hypothetical protein -
ICHIJ1_RS09190 1829140..1829370 + 231 WP_162050317.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ICHIJ1_RS09195 1829360..1829695 + 336 WP_162050318.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
ICHIJ1_RS09200 1829707..1829862 - 156 WP_162050319.1 hypothetical protein -
ICHIJ1_RS09205 1829868..1830125 - 258 WP_162050320.1 type II toxin-antitoxin system RelE/ParE family toxin -
ICHIJ1_RS09210 1830112..1830345 - 234 WP_162050321.1 CopG family transcriptional regulator -
ICHIJ1_RS09215 1830511..1831677 - 1167 WP_162050966.1 MFS transporter -
ICHIJ1_RS09220 1831712..1833103 - 1392 WP_162050322.1 cysteine--tRNA ligase -
ICHIJ1_RS09225 1833236..1833733 + 498 WP_162050323.1 peptidylprolyl isomerase -
ICHIJ1_RS09230 1833730..1834452 + 723 WP_162050324.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-102)

Antitoxin

SpoVT-AbrB domain

(6-47)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12292.22 Da        Isoelectric Point: 10.7556

>T35406 WP_162050318.1 NZ_AP022347:1829360-1829695 [Fluviibacter phosphoraccumulans]
VGFEQFDVVRVPFPFTDRTATKNRPALVLSQSVFSNAADHSVLVMVTSAMNDWPLDCPIKDLQAAGLPAPSRIRFKLFTL
DNRLIRGKIGALSAADRQAFKKQFDRLVATS

Download         Length: 336 bp

>T35406 NZ_AP022347:1829360-1829695 [Fluviibacter phosphoraccumulans]
GTGGGCTTTGAACAATTCGACGTGGTCAGAGTGCCCTTCCCGTTCACGGATCGTACTGCTACTAAAAACAGACCTGCACT
GGTTCTCTCTCAATCCGTCTTTAGTAATGCAGCAGACCATTCAGTGCTTGTGATGGTCACCTCGGCGATGAATGATTGGC
CTTTGGACTGCCCCATAAAAGACCTGCAAGCCGCAGGTTTGCCAGCACCCTCAAGAATCCGCTTCAAACTCTTCACGCTC
GACAACAGACTGATACGAGGAAAGATTGGTGCACTTTCCGCCGCTGATAGACAAGCATTCAAAAAGCAATTTGATCGATT
GGTCGCAACAAGCTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8480.50 Da        Isoelectric Point: 4.1954

>AT35406 WP_162050317.1 NZ_AP022347:1829140-1829370 [Fluviibacter phosphoraccumulans]
MPAIAKITSKGQTTIPAEVRESLNFNPGDLLEWEVNADGSARVRRIQPLDLEYMRAVEGTLTEWGCAEDEEAYRGL

Download         Length: 231 bp

>AT35406 NZ_AP022347:1829140-1829370 [Fluviibacter phosphoraccumulans]
ATGCCAGCTATCGCCAAAATCACCTCAAAAGGCCAAACTACCATTCCAGCAGAGGTCAGAGAGTCGCTTAACTTTAATCC
GGGCGATTTGCTGGAATGGGAAGTGAATGCAGACGGTTCAGCCAGAGTGCGGCGTATTCAACCACTAGACCTAGAGTACA
TGCGCGCCGTTGAAGGCACGCTCACCGAATGGGGCTGCGCGGAAGACGAAGAGGCGTATCGTGGGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References