Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/AbrB(antitoxin) |
Location | 1829140..1829695 | Replicon | chromosome |
Accession | NZ_AP022347 | ||
Organism | Fluviibacter phosphoraccumulans strain ICHIJ1 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | ICHIJ1_RS09195 | Protein ID | WP_162050318.1 |
Coordinates | 1829360..1829695 (+) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | ICHIJ1_RS09190 | Protein ID | WP_162050317.1 |
Coordinates | 1829140..1829370 (+) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ICHIJ1_RS09165 | 1825739..1826884 | + | 1146 | WP_162050312.1 | molecular chaperone DnaJ | - |
ICHIJ1_RS09170 | 1826998..1827549 | - | 552 | WP_162050313.1 | hypothetical protein | - |
ICHIJ1_RS09175 | 1827880..1828209 | - | 330 | WP_162050314.1 | hypothetical protein | - |
ICHIJ1_RS09180 | 1828215..1828694 | - | 480 | WP_162050315.1 | hypothetical protein | - |
ICHIJ1_RS09185 | 1828820..1829056 | - | 237 | WP_162050316.1 | hypothetical protein | - |
ICHIJ1_RS09190 | 1829140..1829370 | + | 231 | WP_162050317.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
ICHIJ1_RS09195 | 1829360..1829695 | + | 336 | WP_162050318.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
ICHIJ1_RS09200 | 1829707..1829862 | - | 156 | WP_162050319.1 | hypothetical protein | - |
ICHIJ1_RS09205 | 1829868..1830125 | - | 258 | WP_162050320.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
ICHIJ1_RS09210 | 1830112..1830345 | - | 234 | WP_162050321.1 | CopG family transcriptional regulator | - |
ICHIJ1_RS09215 | 1830511..1831677 | - | 1167 | WP_162050966.1 | MFS transporter | - |
ICHIJ1_RS09220 | 1831712..1833103 | - | 1392 | WP_162050322.1 | cysteine--tRNA ligase | - |
ICHIJ1_RS09225 | 1833236..1833733 | + | 498 | WP_162050323.1 | peptidylprolyl isomerase | - |
ICHIJ1_RS09230 | 1833730..1834452 | + | 723 | WP_162050324.1 | UDP-2,3-diacylglucosamine diphosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12292.22 Da Isoelectric Point: 10.7556
>T35406 WP_162050318.1 NZ_AP022347:1829360-1829695 [Fluviibacter phosphoraccumulans]
VGFEQFDVVRVPFPFTDRTATKNRPALVLSQSVFSNAADHSVLVMVTSAMNDWPLDCPIKDLQAAGLPAPSRIRFKLFTL
DNRLIRGKIGALSAADRQAFKKQFDRLVATS
VGFEQFDVVRVPFPFTDRTATKNRPALVLSQSVFSNAADHSVLVMVTSAMNDWPLDCPIKDLQAAGLPAPSRIRFKLFTL
DNRLIRGKIGALSAADRQAFKKQFDRLVATS
Download Length: 336 bp
>T35406 NZ_AP022347:1829360-1829695 [Fluviibacter phosphoraccumulans]
GTGGGCTTTGAACAATTCGACGTGGTCAGAGTGCCCTTCCCGTTCACGGATCGTACTGCTACTAAAAACAGACCTGCACT
GGTTCTCTCTCAATCCGTCTTTAGTAATGCAGCAGACCATTCAGTGCTTGTGATGGTCACCTCGGCGATGAATGATTGGC
CTTTGGACTGCCCCATAAAAGACCTGCAAGCCGCAGGTTTGCCAGCACCCTCAAGAATCCGCTTCAAACTCTTCACGCTC
GACAACAGACTGATACGAGGAAAGATTGGTGCACTTTCCGCCGCTGATAGACAAGCATTCAAAAAGCAATTTGATCGATT
GGTCGCAACAAGCTGA
GTGGGCTTTGAACAATTCGACGTGGTCAGAGTGCCCTTCCCGTTCACGGATCGTACTGCTACTAAAAACAGACCTGCACT
GGTTCTCTCTCAATCCGTCTTTAGTAATGCAGCAGACCATTCAGTGCTTGTGATGGTCACCTCGGCGATGAATGATTGGC
CTTTGGACTGCCCCATAAAAGACCTGCAAGCCGCAGGTTTGCCAGCACCCTCAAGAATCCGCTTCAAACTCTTCACGCTC
GACAACAGACTGATACGAGGAAAGATTGGTGCACTTTCCGCCGCTGATAGACAAGCATTCAAAAAGCAATTTGATCGATT
GGTCGCAACAAGCTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8480.50 Da Isoelectric Point: 4.1954
>AT35406 WP_162050317.1 NZ_AP022347:1829140-1829370 [Fluviibacter phosphoraccumulans]
MPAIAKITSKGQTTIPAEVRESLNFNPGDLLEWEVNADGSARVRRIQPLDLEYMRAVEGTLTEWGCAEDEEAYRGL
MPAIAKITSKGQTTIPAEVRESLNFNPGDLLEWEVNADGSARVRRIQPLDLEYMRAVEGTLTEWGCAEDEEAYRGL
Download Length: 231 bp
>AT35406 NZ_AP022347:1829140-1829370 [Fluviibacter phosphoraccumulans]
ATGCCAGCTATCGCCAAAATCACCTCAAAAGGCCAAACTACCATTCCAGCAGAGGTCAGAGAGTCGCTTAACTTTAATCC
GGGCGATTTGCTGGAATGGGAAGTGAATGCAGACGGTTCAGCCAGAGTGCGGCGTATTCAACCACTAGACCTAGAGTACA
TGCGCGCCGTTGAAGGCACGCTCACCGAATGGGGCTGCGCGGAAGACGAAGAGGCGTATCGTGGGCTTTGA
ATGCCAGCTATCGCCAAAATCACCTCAAAAGGCCAAACTACCATTCCAGCAGAGGTCAGAGAGTCGCTTAACTTTAATCC
GGGCGATTTGCTGGAATGGGAAGTGAATGCAGACGGTTCAGCCAGAGTGCGGCGTATTCAACCACTAGACCTAGAGTACA
TGCGCGCCGTTGAAGGCACGCTCACCGAATGGGGCTGCGCGGAAGACGAAGAGGCGTATCGTGGGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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