35405

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1677745..1678360 Replicon chromosome
Accession NZ_AP022347
Organism Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ICHIJ1_RS08380 Protein ID WP_162050169.1
Coordinates 1678055..1678360 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ICHIJ1_RS08375 Protein ID WP_162050168.1
Coordinates 1677745..1678062 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIJ1_RS08350 1672988..1674119 - 1132 Protein_1635 IS3 family transposase -
ICHIJ1_RS08355 1674387..1674860 + 474 WP_202930661.1 tyrosine-type recombinase/integrase -
ICHIJ1_RS08360 1675129..1676151 + 1023 WP_162050165.1 hypothetical protein -
ICHIJ1_RS08365 1676241..1676843 + 603 WP_162050166.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
ICHIJ1_RS08370 1676840..1677679 + 840 WP_162050167.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
ICHIJ1_RS08375 1677745..1678062 - 318 WP_162050168.1 putative addiction module antidote protein Antitoxin
ICHIJ1_RS08380 1678055..1678360 - 306 WP_162050169.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICHIJ1_RS08385 1678714..1679943 + 1230 WP_162050170.1 IS256 family transposase -
ICHIJ1_RS08390 1680002..1680376 + 375 WP_162050171.1 hypothetical protein -
ICHIJ1_RS08395 1680451..1681779 + 1329 WP_162050172.1 TolC family protein -
ICHIJ1_RS08400 1681790..1682350 + 561 WP_162050173.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1674900..1749928 75028
- flank IS/Tn - - 1678714..1679943 1229


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(51-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11471.35 Da        Isoelectric Point: 9.9485

>T35405 WP_162050169.1 NZ_AP022347:c1678360-1678055 [Fluviibacter phosphoraccumulans]
MYTVIQIPAFSDWLRAIKDRQTQVRLMKRLRKAQLGNLGDVKQVGSGVWEMREFFGPGWRMYYVQRGDLLIVMLGGGDKS
TQTADIAKAISLASLVEIEHD

Download         Length: 306 bp

>T35405 NZ_AP022347:c1678360-1678055 [Fluviibacter phosphoraccumulans]
ATGTACACCGTTATACAAATCCCGGCCTTTTCTGATTGGCTCCGAGCCATTAAAGATCGCCAGACACAGGTTCGTCTAAT
GAAGCGCCTTCGTAAAGCGCAATTAGGTAATCTGGGGGATGTTAAACAGGTGGGCAGTGGTGTTTGGGAGATGCGGGAGT
TTTTCGGCCCCGGCTGGCGCATGTACTACGTTCAGCGTGGGGATTTGTTGATCGTGATGCTGGGTGGTGGAGATAAATCT
ACTCAAACAGCAGACATTGCTAAAGCCATTTCTCTTGCGAGCCTGGTGGAGATTGAACATGACTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11516.30 Da        Isoelectric Point: 5.1568

>AT35405 WP_162050168.1 NZ_AP022347:c1678062-1677745 [Fluviibacter phosphoraccumulans]
MTKKIKLADCRPFDIAEYLDDETMITEYMNVVLEENDPAMLASALGDIARARGMSQLAKETGLSRESLYKGLSGDRIPST
ETLLKVIHALGFKLSVSKVDTVAHA

Download         Length: 318 bp

>AT35405 NZ_AP022347:c1678062-1677745 [Fluviibacter phosphoraccumulans]
ATGACTAAGAAGATTAAACTTGCCGATTGCCGACCATTTGATATTGCAGAATATCTGGACGACGAAACCATGATTACAGA
GTATATGAACGTTGTGCTTGAAGAGAACGACCCAGCGATGTTGGCTTCAGCCTTGGGCGATATCGCTCGTGCTCGTGGCA
TGTCACAACTTGCGAAAGAGACTGGCCTCAGCAGAGAAAGCTTATACAAGGGGTTGTCTGGTGACCGTATCCCAAGTACC
GAGACCCTGCTAAAAGTCATTCATGCGCTGGGATTCAAGCTATCAGTATCCAAGGTGGATACAGTCGCGCACGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References