35404

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1676241..1677679 Replicon chromosome
Accession NZ_AP022347
Organism Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag ICHIJ1_RS08370 Protein ID WP_162050167.1
Coordinates 1676840..1677679 (+) Length 280 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag ICHIJ1_RS08365 Protein ID WP_162050166.1
Coordinates 1676241..1676843 (+) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIJ1_RS08340 1671561..1672661 - 1101 WP_162050163.1 P-type DNA transfer ATPase VirB11 -
ICHIJ1_RS08345 1672665..1672946 - 282 WP_162050164.1 hypothetical protein -
ICHIJ1_RS08350 1672988..1674119 - 1132 Protein_1635 IS3 family transposase -
ICHIJ1_RS08355 1674387..1674860 + 474 WP_202930661.1 tyrosine-type recombinase/integrase -
ICHIJ1_RS08360 1675129..1676151 + 1023 WP_162050165.1 hypothetical protein -
ICHIJ1_RS08365 1676241..1676843 + 603 WP_162050166.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
ICHIJ1_RS08370 1676840..1677679 + 840 WP_162050167.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ICHIJ1_RS08375 1677745..1678062 - 318 WP_162050168.1 putative addiction module antidote protein -
ICHIJ1_RS08380 1678055..1678360 - 306 WP_162050169.1 type II toxin-antitoxin system RelE/ParE family toxin -
ICHIJ1_RS08385 1678714..1679943 + 1230 WP_162050170.1 IS256 family transposase -
ICHIJ1_RS08390 1680002..1680376 + 375 WP_162050171.1 hypothetical protein -
ICHIJ1_RS08395 1680451..1681779 + 1329 WP_162050172.1 TolC family protein -
ICHIJ1_RS08400 1681790..1682350 + 561 WP_162050173.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1674900..1749928 75028
- flank IS/Tn - - 1678714..1679943 1229


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(17-53)


Sequences

Toxin        


Download         Length: 280 a.a.        Molecular weight: 31236.08 Da        Isoelectric Point: 4.5766

>T35404 WP_162050167.1 NZ_AP022347:1676840-1677679 [Fluviibacter phosphoraccumulans]
MINRAASVRARLLAKAKAESQDFSLVLTRYGLERLLYRLSVSSNKDNFLLKGALLFDLWFDVPLRPTRDIDLLGFGPAEE
PLVLGAFQEICQIECDDGIEFDLDTLKIEEIRKDANYSGLRISLTGYVDGARCPIQVDIGYGDAVTPAPETAEYPVMLPD
TPVPILRVYPRYTVIAEKLEALIFLGMINTRLKDYFDLWVILTTTELDQNLLGEAITATLVRRKTALPASMPVGLSEEFS
SDAQKIAQWNAFVKKNQLNAPSLDVVVTILRDRFAQFVS

Download         Length: 840 bp

>T35404 NZ_AP022347:1676840-1677679 [Fluviibacter phosphoraccumulans]
ATGATCAATCGTGCCGCATCTGTTCGCGCTCGTTTGTTGGCCAAAGCCAAGGCCGAGAGCCAGGATTTCTCATTGGTGCT
AACCCGCTACGGACTTGAGCGTCTGCTATACCGTTTGAGCGTGTCTTCGAACAAAGACAACTTTTTACTCAAGGGTGCTC
TGCTGTTCGATTTGTGGTTCGACGTGCCGCTACGCCCCACCCGCGATATCGATTTGCTTGGGTTTGGTCCAGCCGAAGAG
CCTTTGGTATTGGGAGCGTTTCAGGAGATATGCCAGATTGAGTGCGACGATGGCATTGAGTTTGATCTCGACACCCTGAA
AATCGAGGAAATTCGAAAGGACGCCAATTATTCCGGGCTACGTATCAGTTTGACTGGATACGTCGATGGGGCACGCTGCC
CCATCCAGGTCGACATCGGCTACGGTGACGCCGTAACGCCAGCGCCTGAAACAGCGGAATATCCAGTCATGTTGCCGGAC
ACCCCAGTGCCGATACTTCGGGTCTATCCTCGGTATACGGTCATCGCTGAGAAATTAGAAGCACTGATCTTTCTGGGAAT
GATCAATACCCGACTTAAGGACTATTTCGACTTATGGGTCATTCTCACTACTACTGAGTTAGACCAAAACTTACTCGGTG
AAGCTATTACCGCAACCTTGGTTCGCAGAAAAACGGCGCTTCCAGCATCGATGCCCGTGGGCCTGTCAGAGGAGTTTTCT
TCTGATGCCCAGAAGATCGCCCAGTGGAACGCATTCGTTAAGAAAAACCAGCTCAATGCGCCGAGCCTTGATGTCGTTGT
TACCATTTTGCGCGACAGGTTCGCTCAATTTGTAAGTTAA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22378.14 Da        Isoelectric Point: 10.3044

>AT35404 WP_162050166.1 NZ_AP022347:1676241-1676843 [Fluviibacter phosphoraccumulans]
MKRQAHPVHQLLTQKTLLRPKDAVSSGYSRIYLAQLAKRGALRKVGRGLYASPLRKESEESGLAEVAMKYPRAVVCLLSA
LSVHGLTTQAPHEVWVAVGSKDRAPKMDYPPLRVVRFGGETLTEGSEVKVVEGIPVQITNVPKTIADCFKFRNKIGLDVA
LEALKEAWRDKRVSIDDLWRYAQLCRVQNVMRPYLESLVA

Download         Length: 603 bp

>AT35404 NZ_AP022347:1676241-1676843 [Fluviibacter phosphoraccumulans]
ATGAAAAGGCAAGCACACCCCGTCCACCAGCTACTGACGCAAAAGACGCTACTCCGTCCCAAAGACGCGGTATCAAGCGG
CTATTCGCGTATTTATCTGGCTCAGCTGGCCAAACGTGGTGCACTACGTAAGGTCGGCCGAGGGCTGTATGCCTCCCCGC
TGCGCAAAGAGTCAGAAGAGTCCGGCCTCGCCGAAGTGGCCATGAAATATCCACGGGCCGTTGTCTGCCTGCTGTCTGCC
CTGTCTGTTCATGGGCTCACAACCCAGGCACCCCACGAAGTATGGGTGGCCGTGGGTAGTAAGGATCGCGCCCCAAAAAT
GGATTATCCACCTCTCCGAGTCGTTCGCTTCGGAGGAGAAACACTAACAGAGGGGTCCGAGGTGAAGGTGGTTGAGGGCA
TCCCTGTTCAAATCACCAATGTTCCCAAGACGATTGCAGATTGCTTCAAGTTCCGCAACAAGATTGGCCTGGACGTAGCA
CTGGAAGCGCTGAAGGAGGCTTGGCGGGATAAGCGCGTCAGCATCGATGATCTGTGGCGTTACGCACAGCTATGTCGCGT
ACAGAATGTCATGCGCCCCTACCTTGAAAGCCTGGTCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References