Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1500970..1501571 Replicon chromosome
Accession NZ_AP022347
Organism Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ICHIJ1_RS07495 Protein ID WP_162050014.1
Coordinates 1501266..1501571 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ICHIJ1_RS07490 Protein ID WP_162050013.1
Coordinates 1500970..1501269 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIJ1_RS07460 1496639..1497328 + 690 WP_174237203.1 electron transport complex subunit E -
ICHIJ1_RS07465 1497341..1498000 + 660 WP_162050009.1 endonuclease III -
ICHIJ1_RS07470 1498017..1498439 + 423 WP_162050942.1 DUF1841 family protein -
ICHIJ1_RS07475 1498521..1499258 - 738 WP_162050010.1 3-ketoacyl-ACP reductase -
ICHIJ1_RS07480 1499413..1500630 + 1218 WP_162050011.1 MFS transporter -
ICHIJ1_RS07485 1500635..1500946 + 312 WP_162050012.1 hypothetical protein -
ICHIJ1_RS07490 1500970..1501269 - 300 WP_162050013.1 putative addiction module antidote protein Antitoxin
ICHIJ1_RS07495 1501266..1501571 - 306 WP_162050014.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICHIJ1_RS07500 1501841..1502062 - 222 WP_202930672.1 DUF4224 domain-containing protein -
ICHIJ1_RS07505 1502297..1502572 - 276 WP_162050015.1 hypothetical protein -
ICHIJ1_RS07510 1502918..1503583 + 666 WP_162050016.1 hypothetical protein -
ICHIJ1_RS07520 1504963..1505307 - 345 WP_202930671.1 DUF86 domain-containing protein -
ICHIJ1_RS07525 1505304..1505594 - 291 WP_162050018.1 nucleotidyltransferase family protein -
ICHIJ1_RS07535 1505787..1506107 - 321 WP_162050019.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-92)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11439.08 Da        Isoelectric Point: 9.9574

>T35403 WP_162050014.1 NZ_AP022347:c1501571-1501266 [Fluviibacter phosphoraccumulans]
MKLIYTTEIFDAWFGRLKDKEVARRIQIRIDRAEDGHFGDCKSVGGGVSEMRIHHGPGYRVYFMQRGFEVVILLAGGDKS
SQSRDIQTAIHIAQQIKGSRS

Download         Length: 306 bp

>T35403 NZ_AP022347:c1501571-1501266 [Fluviibacter phosphoraccumulans]
ATGAAACTTATCTATACGACAGAAATTTTTGATGCTTGGTTTGGCCGATTAAAAGACAAAGAAGTTGCGCGGCGGATTCA
GATTCGGATCGACAGAGCAGAAGATGGTCATTTCGGAGACTGTAAGTCTGTTGGTGGCGGTGTTTCAGAAATGCGAATTC
ATCATGGGCCGGGATATCGGGTGTATTTCATGCAACGAGGATTCGAGGTGGTGATTTTACTAGCAGGTGGTGACAAGTCA
TCACAGTCCAGAGATATTCAAACAGCTATACATATAGCTCAGCAGATTAAGGGTAGCAGATCATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10721.36 Da        Isoelectric Point: 7.2776

>AT35403 WP_162050013.1 NZ_AP022347:c1501269-1500970 [Fluviibacter phosphoraccumulans]
MKAVKLRRWDSAEHLKTSEEMALYLEACFQEAGDDAAFIAKALGNIARAKGMSQLAQETGMGRESLYKALSGEGNPSFAT
ILKVTRALGIELHAMPVHA

Download         Length: 300 bp

>AT35403 NZ_AP022347:c1501269-1500970 [Fluviibacter phosphoraccumulans]
ATGAAAGCAGTAAAGCTACGTAGATGGGATAGCGCCGAACATCTGAAAACATCAGAAGAGATGGCGTTGTATCTAGAAGC
TTGCTTCCAAGAAGCAGGTGATGATGCTGCATTTATTGCCAAAGCACTGGGTAACATTGCACGTGCCAAAGGCATGTCAC
AGCTAGCCCAAGAGACCGGTATGGGACGGGAGAGTCTTTATAAAGCGCTCTCCGGAGAAGGTAACCCAAGCTTTGCAACC
ATTCTCAAGGTGACACGTGCTTTAGGTATTGAGCTTCATGCGATGCCAGTTCATGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References