Detailed information of TA system TA035401

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1199028..1199547
• Replicon: chromosome
• Accession: NZ_AP022347
• Organism: Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ICHIJ1_RS06110
• Protein ID: WP_162049771.1
• Coordinates: 1199260..1199547 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ICHIJ1_RS06105
• Protein ID: WP_162049770.1
• Coordinates: 1199028..1199273 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIJ1_RS06085	1194339..1196453	+	2115	WP_162050918.1	polyribonucleotide nucleotidyltransferase	-
ICHIJ1_RS06090	1196558..1196920	-	363	WP_202930777.1	RNA polymerase-binding protein DksA	-
ICHIJ1_RS06095	1197253..1197510	+	258	WP_162049768.1	hypothetical protein	-
ICHIJ1_RS06100	1197516..1198964	+	1449	WP_162049769.1	YdiU family protein	-
ICHIJ1_RS06105	1199028..1199273	+	246	WP_162049770.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ICHIJ1_RS06110	1199260..1199547	+	288	WP_162049771.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ICHIJ1_RS06115	1199651..1199929	+	279	WP_162049772.1	hypothetical protein	-
ICHIJ1_RS06120	1199958..1200395	+	438	WP_162049773.1	nucleoside deaminase	-
ICHIJ1_RS06125	1200642..1201013	+	372	WP_202930689.1	hypothetical protein	-
ICHIJ1_RS06130	1201010..1201357	+	348	WP_162049774.1	transcriptional regulator	-
ICHIJ1_RS06135	1201460..1203619	+	2160	WP_202930688.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10969.05 Da
• Isoelectric Point: 10.4134

>T35401 WP_162049771.1 NZ_AP022347:1199260-1199547 [Fluviibacter phosphoraccumulans]
MPTYKLQFHQLALAEWKKLDKTVRDPLIKKLTERLENPRVPAAALIGMPDCYKIKIHSLGYRLVYRVDDGVVYVTVIAVG
KRERSAVYKTALQRL

Nucleotide

• Length: 288 bp

>T35401 NZ_AP022347:1199260-1199547 [Fluviibacter phosphoraccumulans]
TTGCCGACTTATAAACTACAGTTTCACCAGCTTGCATTAGCAGAATGGAAGAAGCTTGATAAAACGGTACGTGACCCACT
AATCAAAAAGCTAACCGAGCGCTTGGAGAACCCACGTGTGCCGGCAGCGGCACTGATTGGTATGCCCGATTGCTACAAAA
TCAAAATACATTCGCTTGGCTATCGTTTGGTATATCGCGTGGATGATGGTGTGGTCTACGTCACGGTCATCGCTGTTGGC
AAGCGGGAAAGAAGCGCGGTATACAAGACTGCCCTTCAGCGCCTTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9118.32 Da
• Isoelectric Point: 4.3176

>AT35401 WP_162049770.1 NZ_AP022347:1199028-1199273 [Fluviibacter phosphoraccumulans]
MDNILATMSVSVTELKRNYASIIKDADDSPVAVLNHNRPEAYLLPAGHYERLMSYLEDLEDAKLVRERANGPFVEIDLAD
L

Nucleotide

• Length: 246 bp

>AT35401 NZ_AP022347:1199028-1199273 [Fluviibacter phosphoraccumulans]
ATGGACAACATACTTGCAACAATGAGTGTTAGTGTTACCGAGTTAAAGCGAAATTACGCCTCGATTATCAAAGATGCCGA
TGATAGTCCTGTGGCTGTGCTAAATCATAATCGTCCAGAGGCTTATCTGCTTCCTGCGGGGCATTACGAGCGACTTATGA
GCTATCTCGAAGACTTAGAAGATGCTAAGTTGGTCCGAGAAAGAGCGAACGGGCCATTTGTAGAGATTGATCTTGCCGAC
TTATAA