Detailed information of TA system TA035400

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1096401..1096945
• Replicon: chromosome
• Accession: NZ_AP022347
• Organism: Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ICHIJ1_RS05630
• Protein ID: WP_162049681.1
• Coordinates: 1096667..1096945 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ICHIJ1_RS05625
• Protein ID: WP_162049680.1
• Coordinates: 1096401..1096667 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIJ1_RS05595	1092099..1092758	+	660	WP_162049676.1	transcriptional regulator	-
ICHIJ1_RS05600	1092984..1093244	+	261	WP_162049677.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIJ1_RS05605	1093244..1093510	+	267	WP_162049678.1	Txe/YoeB family addiction module toxin	-
ICHIJ1_RS05610	1093579..1094049	+	471	WP_162049679.1	hypothetical protein	-
ICHIJ1_RS05615	1094068..1095015	+	948	WP_202930691.1	hypothetical protein	-
ICHIJ1_RS05620	1095030..1096334	+	1305	WP_202930690.1	glycosyltransferase family 4 protein	-
ICHIJ1_RS05625	1096401..1096667	+	267	WP_162049680.1	ribbon-helix-helix protein, CopG family	Antitoxin
ICHIJ1_RS05630	1096667..1096945	+	279	WP_162049681.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ICHIJ1_RS05635	1096952..1097551	+	600	WP_162049682.1	adenylyl-sulfate kinase	-
ICHIJ1_RS05640	1097554..1098354	+	801	WP_162049683.1	3'(2'),5'-bisphosphate nucleotidase CysQ	-
ICHIJ1_RS05645	1098347..1099126	+	780	WP_162049684.1	sulfite exporter TauE/SafE family protein	-
ICHIJ1_RS05650	1099177..1101012	+	1836	WP_162049685.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	gmd / fcl	1058849..1102748	43899

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10707.55 Da
• Isoelectric Point: 10.7462

>T35400 WP_162049681.1 NZ_AP022347:1096667-1096945 [Fluviibacter phosphoraccumulans]
MVKVAWTRHAVQDLGRLHEFLKVVNPTAAAKILQNLVKAPSALIGNPRMGERIEAFESREIRRLLVARYELRYEIKDATL
YILRIGHTREER

Nucleotide

• Length: 279 bp

>T35400 NZ_AP022347:1096667-1096945 [Fluviibacter phosphoraccumulans]
ATGGTTAAGGTTGCATGGACGCGCCACGCGGTTCAGGATTTGGGTCGGCTCCATGAGTTTCTCAAAGTCGTCAACCCGAC
AGCGGCAGCTAAGATCCTACAGAATCTGGTGAAAGCACCGAGTGCACTGATCGGAAATCCTCGGATGGGGGAGCGAATAG
AAGCCTTTGAGTCACGCGAAATTCGCCGCTTGTTGGTCGCTCGATACGAATTGCGATATGAAATTAAGGATGCCACGCTT
TATATTTTGCGGATCGGGCATACACGAGAAGAACGGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9960.16 Da
• Isoelectric Point: 4.1649

>AT35400 WP_162049680.1 NZ_AP022347:1096401-1096667 [Fluviibacter phosphoraccumulans]
MANLETKVLTAHVPIDLADKVDYLAERLDRSRGWVVKQALAAWVDQEEERTRLTEEAMADVDQENLVAHESMLAWADSLD
TETPRALP

Nucleotide

• Length: 267 bp

>AT35400 NZ_AP022347:1096401-1096667 [Fluviibacter phosphoraccumulans]
ATGGCAAACCTAGAAACCAAAGTCCTGACTGCGCACGTTCCGATCGATCTTGCTGATAAGGTGGATTATCTGGCGGAACG
ATTGGATCGCTCCCGCGGTTGGGTAGTTAAACAGGCGCTCGCGGCGTGGGTTGATCAGGAAGAAGAGCGAACCCGTCTGA
CCGAAGAGGCCATGGCTGATGTTGACCAAGAAAATCTGGTAGCCCATGAGAGTATGCTGGCATGGGCAGATAGCCTTGAT
ACAGAAACCCCACGGGCACTCCCTTAA