Detailed information of TA system TA035392

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 327307..327868
• Replicon: chromosome
• Accession: NZ_AP022347
• Organism: Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ICHIJ1_RS01720
• Protein ID: WP_162049012.1
• Coordinates: 327307..327612 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ICHIJ1_RS01725
• Protein ID: WP_162049013.1
• Coordinates: 327617..327868 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIJ1_RS01690	322558..323598	-	1041	WP_162049006.1	glycosyltransferase family 9 protein	-
ICHIJ1_RS01695	323639..324697	+	1059	WP_162049007.1	glycosyltransferase family 9 protein	-
ICHIJ1_RS01700	324683..325024	-	342	WP_162049008.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ICHIJ1_RS01705	325021..325296	-	276	WP_162049009.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIJ1_RS01710	325357..326703	-	1347	WP_162049010.1	type II toxin-antitoxin system HipA family toxin YjjJ	-
ICHIJ1_RS01715	326994..327236	-	243	WP_162049011.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIJ1_RS01720	327307..327612	-	306	WP_162049012.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ICHIJ1_RS01725	327617..327868	-	252	WP_162049013.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ICHIJ1_RS01730	328221..328919	-	699	WP_162049014.1	toll/interleukin-1 receptor domain-containing protein	-
ICHIJ1_RS01735	329376..329966	+	591	WP_162049015.1	GNAT family N-acetyltransferase	-
ICHIJ1_RS01740	330148..330714	-	567	WP_202930727.1	hypothetical protein	-
ICHIJ1_RS01745	330711..332015	-	1305	WP_162049016.1	dNTP triphosphohydrolase	-
ICHIJ1_RS01750	332167..332598	-	432	WP_162049017.1	transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-70)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11449.62 Da
• Isoelectric Point: 10.2841

>T35392 WP_162049012.1 NZ_AP022347:c327612-327307 [Fluviibacter phosphoraccumulans]
VAYRLQFLPEALKEWEALDGSIKAPLRAALKKRLENPHVPSAVLGSELAGCYKIKLRKQGYRLVYVVEDDVLVVIVLAIG
KRERLATYEYALKRLITKRVG

Nucleotide

• Length: 306 bp

>T35392 NZ_AP022347:c327612-327307 [Fluviibacter phosphoraccumulans]
GTGGCTTACCGCCTGCAGTTTCTGCCCGAGGCTTTGAAAGAGTGGGAGGCGCTCGATGGCAGTATCAAAGCGCCACTCCG
AGCTGCCCTGAAAAAACGGCTGGAGAATCCACACGTCCCGAGTGCGGTGCTTGGATCAGAACTTGCTGGTTGCTACAAAA
TCAAACTTCGCAAGCAAGGGTATCGCCTCGTCTACGTGGTTGAAGATGATGTTCTAGTAGTAATTGTGCTGGCCATCGGC
AAACGAGAGCGGCTGGCTACTTACGAGTATGCCCTTAAGCGGTTGATAACGAAGCGGGTTGGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9397.70 Da
• Isoelectric Point: 4.7335

>AT35392 WP_162049013.1 NZ_AP022347:c327868-327617 [Fluviibacter phosphoraccumulans]
MDTIYADYSVSMSEFKKNPAQVLRTAGEKPVAVLSHNRPAFYMVTPQLFESLVEELADHDLIDIVRDRLTRKTTAVDVDI
NSI

Nucleotide

• Length: 252 bp

>AT35392 NZ_AP022347:c327868-327617 [Fluviibacter phosphoraccumulans]
ATGGATACCATTTACGCAGATTACTCAGTGAGCATGTCCGAGTTCAAGAAGAACCCGGCTCAAGTGCTGCGCACCGCAGG
TGAAAAGCCCGTGGCAGTTTTGAGCCATAACCGCCCTGCTTTTTACATGGTGACGCCACAGCTATTTGAATCTCTGGTTG
AAGAGCTGGCTGATCACGATTTGATCGACATCGTTCGAGATCGCTTAACGCGCAAAACCACAGCCGTCGACGTCGACATC
AACAGTATTTAA