Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | slvAT/RES(toxin) |
Location | 1971196..1972121 | Replicon | chromosome |
Accession | NZ_AP022345 | ||
Organism | Fluviibacter phosphoraccumulans strain ICHIAU1 |
Toxin (Protein)
Gene name | slvT | Uniprot ID | - |
Locus tag | ICHIAU1_RS09815 | Protein ID | WP_202930692.1 |
Coordinates | 1971196..1971678 (-) | Length | 161 a.a. |
Antitoxin (Protein)
Gene name | slvA | Uniprot ID | - |
Locus tag | ICHIAU1_RS09820 | Protein ID | WP_162049659.1 |
Coordinates | 1971714..1972121 (-) | Length | 136 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ICHIAU1_RS09785 | 1966453..1966800 | - | 348 | WP_162049666.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
ICHIAU1_RS09790 | 1966847..1968088 | - | 1242 | WP_162049665.1 | hypothetical protein | - |
ICHIAU1_RS09795 | 1968139..1970097 | - | 1959 | WP_162049664.1 | ATP-binding protein | - |
ICHIAU1_RS09800 | 1970177..1970569 | - | 393 | WP_162049663.1 | hypothetical protein | - |
ICHIAU1_RS09805 | 1970541..1970732 | - | 192 | WP_162049662.1 | hypothetical protein | - |
ICHIAU1_RS09810 | 1970875..1971183 | - | 309 | WP_162049661.1 | HigA family addiction module antidote protein | - |
ICHIAU1_RS09815 | 1971196..1971678 | - | 483 | WP_202930692.1 | RES family NAD+ phosphorylase | Toxin |
ICHIAU1_RS09820 | 1971714..1972121 | - | 408 | WP_162049659.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
ICHIAU1_RS09825 | 1972192..1973052 | - | 861 | WP_162049658.1 | hypothetical protein | - |
ICHIAU1_RS09830 | 1973059..1975590 | - | 2532 | WP_162049657.1 | S8 family peptidase | - |
ICHIAU1_RS09835 | 1975568..1976620 | - | 1053 | WP_162049656.1 | ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fcl / gmd | 1951104..1994441 | 43337 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 17073.12 Da Isoelectric Point: 4.4067
>T35391 WP_202930692.1 NZ_AP022345:c1971678-1971196 [Fluviibacter phosphoraccumulans]
MHAPKWAVAPTSGAGAGKHGGRANRPGIDAIYLALETQTAINEYQQTSTLLPPGTLTSYKLSAAPVVDFTGGYSASVWEP
IWEDFYCDWRELWFNQGVEPPSWIAADLALAAGAKGILFSSRLAAGGTNLVLFNSSLVAPDFLDVYDPGNALPQNQASWS
MHAPKWAVAPTSGAGAGKHGGRANRPGIDAIYLALETQTAINEYQQTSTLLPPGTLTSYKLSAAPVVDFTGGYSASVWEP
IWEDFYCDWRELWFNQGVEPPSWIAADLALAAGAKGILFSSRLAAGGTNLVLFNSSLVAPDFLDVYDPGNALPQNQASWS
Download Length: 483 bp
>T35391 NZ_AP022345:c1971678-1971196 [Fluviibacter phosphoraccumulans]
ATGCACGCTCCCAAGTGGGCTGTTGCACCTACCAGCGGTGCTGGAGCTGGTAAACATGGTGGCCGTGCCAATCGGCCAGG
TATTGATGCCATTTATTTGGCGCTAGAGACTCAGACGGCTATTAATGAGTACCAACAGACTTCAACTTTGTTGCCACCCG
GCACGTTAACCAGTTACAAATTGTCTGCCGCGCCCGTTGTAGATTTTACCGGCGGGTACAGCGCCTCGGTATGGGAGCCA
ATTTGGGAAGACTTCTACTGCGACTGGCGCGAGCTCTGGTTTAATCAGGGGGTCGAGCCTCCTAGCTGGATTGCAGCAGA
TTTGGCTTTAGCTGCGGGTGCAAAGGGGATTCTCTTTTCTTCGCGGTTAGCTGCTGGCGGAACGAATCTCGTGCTGTTTA
ATAGCTCGCTGGTCGCTCCTGATTTCTTAGACGTTTATGATCCGGGTAATGCTTTGCCACAGAACCAGGCGTCATGGTCT
TGA
ATGCACGCTCCCAAGTGGGCTGTTGCACCTACCAGCGGTGCTGGAGCTGGTAAACATGGTGGCCGTGCCAATCGGCCAGG
TATTGATGCCATTTATTTGGCGCTAGAGACTCAGACGGCTATTAATGAGTACCAACAGACTTCAACTTTGTTGCCACCCG
GCACGTTAACCAGTTACAAATTGTCTGCCGCGCCCGTTGTAGATTTTACCGGCGGGTACAGCGCCTCGGTATGGGAGCCA
ATTTGGGAAGACTTCTACTGCGACTGGCGCGAGCTCTGGTTTAATCAGGGGGTCGAGCCTCCTAGCTGGATTGCAGCAGA
TTTGGCTTTAGCTGCGGGTGCAAAGGGGATTCTCTTTTCTTCGCGGTTAGCTGCTGGCGGAACGAATCTCGTGCTGTTTA
ATAGCTCGCTGGTCGCTCCTGATTTCTTAGACGTTTATGATCCGGGTAATGCTTTGCCACAGAACCAGGCGTCATGGTCT
TGA
Antitoxin
Download Length: 136 a.a. Molecular weight: 15008.97 Da Isoelectric Point: 7.2772
>AT35391 WP_162049659.1 NZ_AP022345:c1972121-1971714 [Fluviibacter phosphoraccumulans]
MTATLVQKSKALSCGFDGFIDFLHDQEAGPSTLSPKRFGDVLKIDLQTLATQAHVHRNTITRAPASESVQKYLREALRVL
RAANDLSGDVTRAIFWYRNEPLPPFRYKTAEQLVSEGRTEDVLRYVESLEAGAAG
MTATLVQKSKALSCGFDGFIDFLHDQEAGPSTLSPKRFGDVLKIDLQTLATQAHVHRNTITRAPASESVQKYLREALRVL
RAANDLSGDVTRAIFWYRNEPLPPFRYKTAEQLVSEGRTEDVLRYVESLEAGAAG
Download Length: 408 bp
>AT35391 NZ_AP022345:c1972121-1971714 [Fluviibacter phosphoraccumulans]
ATGACCGCAACACTCGTACAGAAATCCAAGGCCTTAAGCTGTGGTTTTGATGGTTTCATCGATTTTTTGCATGATCAGGA
AGCGGGGCCTTCTACCTTGTCGCCCAAGCGCTTTGGTGATGTGCTCAAGATAGATTTGCAGACGCTTGCAACGCAGGCGC
ATGTTCATCGCAATACCATCACCCGTGCGCCAGCATCTGAAAGCGTGCAGAAGTATCTGCGAGAGGCATTGCGCGTTCTG
CGTGCTGCCAATGATTTATCTGGTGACGTAACACGTGCCATCTTCTGGTATCGCAACGAGCCTTTGCCGCCGTTTCGGTA
TAAGACCGCTGAGCAATTGGTCTCTGAAGGGCGTACCGAAGATGTGCTGCGCTATGTTGAGTCGCTGGAAGCTGGTGCCG
CCGGGTGA
ATGACCGCAACACTCGTACAGAAATCCAAGGCCTTAAGCTGTGGTTTTGATGGTTTCATCGATTTTTTGCATGATCAGGA
AGCGGGGCCTTCTACCTTGTCGCCCAAGCGCTTTGGTGATGTGCTCAAGATAGATTTGCAGACGCTTGCAACGCAGGCGC
ATGTTCATCGCAATACCATCACCCGTGCGCCAGCATCTGAAAGCGTGCAGAAGTATCTGCGAGAGGCATTGCGCGTTCTG
CGTGCTGCCAATGATTTATCTGGTGACGTAACACGTGCCATCTTCTGGTATCGCAACGAGCCTTTGCCGCCGTTTCGGTA
TAAGACCGCTGAGCAATTGGTCTCTGAAGGGCGTACCGAAGATGTGCTGCGCTATGTTGAGTCGCTGGAAGCTGGTGCCG
CCGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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