35391

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 1971196..1972121 Replicon chromosome
Accession NZ_AP022345
Organism Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag ICHIAU1_RS09815 Protein ID WP_202930692.1
Coordinates 1971196..1971678 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag ICHIAU1_RS09820 Protein ID WP_162049659.1
Coordinates 1971714..1972121 (-) Length 136 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIAU1_RS09785 1966453..1966800 - 348 WP_162049666.1 type II toxin-antitoxin system RelE/ParE family toxin -
ICHIAU1_RS09790 1966847..1968088 - 1242 WP_162049665.1 hypothetical protein -
ICHIAU1_RS09795 1968139..1970097 - 1959 WP_162049664.1 ATP-binding protein -
ICHIAU1_RS09800 1970177..1970569 - 393 WP_162049663.1 hypothetical protein -
ICHIAU1_RS09805 1970541..1970732 - 192 WP_162049662.1 hypothetical protein -
ICHIAU1_RS09810 1970875..1971183 - 309 WP_162049661.1 HigA family addiction module antidote protein -
ICHIAU1_RS09815 1971196..1971678 - 483 WP_202930692.1 RES family NAD+ phosphorylase Toxin
ICHIAU1_RS09820 1971714..1972121 - 408 WP_162049659.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
ICHIAU1_RS09825 1972192..1973052 - 861 WP_162049658.1 hypothetical protein -
ICHIAU1_RS09830 1973059..1975590 - 2532 WP_162049657.1 S8 family peptidase -
ICHIAU1_RS09835 1975568..1976620 - 1053 WP_162049656.1 ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - fcl / gmd 1951104..1994441 43337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-135)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 161 a.a.        Molecular weight: 17073.12 Da        Isoelectric Point: 4.4067

>T35391 WP_202930692.1 NZ_AP022345:c1971678-1971196 [Fluviibacter phosphoraccumulans]
MHAPKWAVAPTSGAGAGKHGGRANRPGIDAIYLALETQTAINEYQQTSTLLPPGTLTSYKLSAAPVVDFTGGYSASVWEP
IWEDFYCDWRELWFNQGVEPPSWIAADLALAAGAKGILFSSRLAAGGTNLVLFNSSLVAPDFLDVYDPGNALPQNQASWS

Download         Length: 483 bp

>T35391 NZ_AP022345:c1971678-1971196 [Fluviibacter phosphoraccumulans]
ATGCACGCTCCCAAGTGGGCTGTTGCACCTACCAGCGGTGCTGGAGCTGGTAAACATGGTGGCCGTGCCAATCGGCCAGG
TATTGATGCCATTTATTTGGCGCTAGAGACTCAGACGGCTATTAATGAGTACCAACAGACTTCAACTTTGTTGCCACCCG
GCACGTTAACCAGTTACAAATTGTCTGCCGCGCCCGTTGTAGATTTTACCGGCGGGTACAGCGCCTCGGTATGGGAGCCA
ATTTGGGAAGACTTCTACTGCGACTGGCGCGAGCTCTGGTTTAATCAGGGGGTCGAGCCTCCTAGCTGGATTGCAGCAGA
TTTGGCTTTAGCTGCGGGTGCAAAGGGGATTCTCTTTTCTTCGCGGTTAGCTGCTGGCGGAACGAATCTCGTGCTGTTTA
ATAGCTCGCTGGTCGCTCCTGATTTCTTAGACGTTTATGATCCGGGTAATGCTTTGCCACAGAACCAGGCGTCATGGTCT
TGA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 15008.97 Da        Isoelectric Point: 7.2772

>AT35391 WP_162049659.1 NZ_AP022345:c1972121-1971714 [Fluviibacter phosphoraccumulans]
MTATLVQKSKALSCGFDGFIDFLHDQEAGPSTLSPKRFGDVLKIDLQTLATQAHVHRNTITRAPASESVQKYLREALRVL
RAANDLSGDVTRAIFWYRNEPLPPFRYKTAEQLVSEGRTEDVLRYVESLEAGAAG

Download         Length: 408 bp

>AT35391 NZ_AP022345:c1972121-1971714 [Fluviibacter phosphoraccumulans]
ATGACCGCAACACTCGTACAGAAATCCAAGGCCTTAAGCTGTGGTTTTGATGGTTTCATCGATTTTTTGCATGATCAGGA
AGCGGGGCCTTCTACCTTGTCGCCCAAGCGCTTTGGTGATGTGCTCAAGATAGATTTGCAGACGCTTGCAACGCAGGCGC
ATGTTCATCGCAATACCATCACCCGTGCGCCAGCATCTGAAAGCGTGCAGAAGTATCTGCGAGAGGCATTGCGCGTTCTG
CGTGCTGCCAATGATTTATCTGGTGACGTAACACGTGCCATCTTCTGGTATCGCAACGAGCCTTTGCCGCCGTTTCGGTA
TAAGACCGCTGAGCAATTGGTCTCTGAAGGGCGTACCGAAGATGTGCTGCGCTATGTTGAGTCGCTGGAAGCTGGTGCCG
CCGGGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References