Detailed information of TA system TA035387

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1853992..1854511
• Replicon: chromosome
• Accession: NZ_AP022345
• Organism: Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ICHIAU1_RS09220
• Protein ID: WP_162049771.1
• Coordinates: 1853992..1854279 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ICHIAU1_RS09225
• Protein ID: WP_162049770.1
• Coordinates: 1854266..1854511 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIAU1_RS09195	1849920..1852079	-	2160	WP_202930688.1	hypothetical protein	-
ICHIAU1_RS09200	1852182..1852529	-	348	WP_162049774.1	transcriptional regulator	-
ICHIAU1_RS09205	1852526..1852897	-	372	WP_202930689.1	hypothetical protein	-
ICHIAU1_RS09210	1853144..1853581	-	438	WP_162049773.1	nucleoside deaminase	-
ICHIAU1_RS09215	1853610..1853855	-	246	WP_207105415.1	hypothetical protein	-
ICHIAU1_RS09220	1853992..1854279	-	288	WP_162049771.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ICHIAU1_RS09225	1854266..1854511	-	246	WP_162049770.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ICHIAU1_RS09230	1854575..1856023	-	1449	WP_162049769.1	YdiU family protein	-
ICHIAU1_RS09235	1856029..1856286	-	258	WP_162049768.1	hypothetical protein	-
ICHIAU1_RS09240	1856619..1856981	+	363	WP_202930777.1	RNA polymerase-binding protein DksA	-
ICHIAU1_RS09245	1857086..1859200	-	2115	WP_162050918.1	polyribonucleotide nucleotidyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10969.05 Da
• Isoelectric Point: 10.4134

>T35387 WP_162049771.1 NZ_AP022345:c1854279-1853992 [Fluviibacter phosphoraccumulans]
MPTYKLQFHQLALAEWKKLDKTVRDPLIKKLTERLENPRVPAAALIGMPDCYKIKIHSLGYRLVYRVDDGVVYVTVIAVG
KRERSAVYKTALQRL

Nucleotide

• Length: 288 bp

>T35387 NZ_AP022345:c1854279-1853992 [Fluviibacter phosphoraccumulans]
TTGCCGACTTATAAACTACAGTTTCACCAGCTTGCATTAGCAGAATGGAAGAAGCTTGATAAAACGGTACGTGACCCACT
AATCAAAAAGCTAACCGAGCGCTTGGAGAACCCACGTGTGCCGGCAGCGGCACTGATTGGTATGCCCGATTGCTACAAAA
TCAAAATACATTCGCTTGGCTATCGTTTGGTATATCGCGTGGATGATGGTGTGGTCTACGTCACGGTCATCGCTGTTGGC
AAGCGGGAAAGAAGCGCGGTATACAAGACTGCCCTTCAGCGCCTTTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9118.32 Da
• Isoelectric Point: 4.3176

>AT35387 WP_162049770.1 NZ_AP022345:c1854511-1854266 [Fluviibacter phosphoraccumulans]
MDNILATMSVSVTELKRNYASIIKDADDSPVAVLNHNRPEAYLLPAGHYERLMSYLEDLEDAKLVRERANGPFVEIDLAD
L

Nucleotide

• Length: 246 bp

>AT35387 NZ_AP022345:c1854511-1854266 [Fluviibacter phosphoraccumulans]
ATGGACAACATACTTGCAACAATGAGTGTTAGTGTTACCGAGTTAAAGCGAAATTACGCCTCGATTATCAAAGATGCCGA
TGATAGTCCTGTGGCTGTGCTAAATCATAATCGTCCAGAGGCTTATCTGCTTCCTGCGGGGCATTACGAGCGACTTATGA
GCTATCTCGAAGACTTAGAAGATGCTAAGTTGGTCCGAGAAAGAGCGAACGGGCCATTTGTAGAGATTGATCTTGCCGAC
TTATAA