Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/AbrB(antitoxin) |
Location | 1260243..1260798 | Replicon | chromosome |
Accession | NZ_AP022345 | ||
Organism | Fluviibacter phosphoraccumulans strain ICHIAU1 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | ICHIAU1_RS06270 | Protein ID | WP_162050318.1 |
Coordinates | 1260243..1260578 (-) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | ICHIAU1_RS06275 | Protein ID | WP_162050317.1 |
Coordinates | 1260568..1260798 (-) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ICHIAU1_RS06235 | 1255486..1256208 | - | 723 | WP_162050324.1 | UDP-2,3-diacylglucosamine diphosphatase | - |
ICHIAU1_RS06240 | 1256205..1256702 | - | 498 | WP_162050323.1 | peptidylprolyl isomerase | - |
ICHIAU1_RS06245 | 1256835..1258226 | + | 1392 | WP_162050322.1 | cysteine--tRNA ligase | - |
ICHIAU1_RS06250 | 1258261..1259427 | + | 1167 | WP_162050966.1 | MFS transporter | - |
ICHIAU1_RS06255 | 1259593..1259826 | + | 234 | WP_162050321.1 | CopG family transcriptional regulator | - |
ICHIAU1_RS06260 | 1259813..1260070 | + | 258 | WP_162050320.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
ICHIAU1_RS06265 | 1260076..1260231 | + | 156 | WP_162050319.1 | hypothetical protein | - |
ICHIAU1_RS06270 | 1260243..1260578 | - | 336 | WP_162050318.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
ICHIAU1_RS06275 | 1260568..1260798 | - | 231 | WP_162050317.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
ICHIAU1_RS06280 | 1260882..1261118 | + | 237 | WP_162050316.1 | hypothetical protein | - |
ICHIAU1_RS06285 | 1261244..1261723 | + | 480 | WP_162050315.1 | hypothetical protein | - |
ICHIAU1_RS06290 | 1261729..1262058 | + | 330 | WP_162050314.1 | hypothetical protein | - |
ICHIAU1_RS06295 | 1262389..1262940 | + | 552 | WP_162050313.1 | hypothetical protein | - |
ICHIAU1_RS06300 | 1263054..1264199 | - | 1146 | WP_162050312.1 | molecular chaperone DnaJ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12292.22 Da Isoelectric Point: 10.7556
>T35382 WP_162050318.1 NZ_AP022345:c1260578-1260243 [Fluviibacter phosphoraccumulans]
VGFEQFDVVRVPFPFTDRTATKNRPALVLSQSVFSNAADHSVLVMVTSAMNDWPLDCPIKDLQAAGLPAPSRIRFKLFTL
DNRLIRGKIGALSAADRQAFKKQFDRLVATS
VGFEQFDVVRVPFPFTDRTATKNRPALVLSQSVFSNAADHSVLVMVTSAMNDWPLDCPIKDLQAAGLPAPSRIRFKLFTL
DNRLIRGKIGALSAADRQAFKKQFDRLVATS
Download Length: 336 bp
>T35382 NZ_AP022345:c1260578-1260243 [Fluviibacter phosphoraccumulans]
GTGGGCTTTGAACAATTCGACGTGGTCAGAGTGCCCTTCCCGTTCACGGATCGTACTGCTACTAAAAACAGACCTGCACT
GGTTCTCTCTCAATCCGTCTTTAGTAATGCAGCAGACCATTCAGTGCTTGTGATGGTCACCTCGGCGATGAATGATTGGC
CTTTGGACTGCCCCATAAAAGACCTGCAAGCCGCAGGTTTGCCAGCACCCTCAAGAATCCGCTTCAAACTCTTCACGCTC
GACAACAGACTGATACGAGGAAAGATTGGTGCACTTTCCGCCGCTGATAGACAAGCATTCAAAAAGCAATTTGATCGATT
GGTCGCAACAAGCTGA
GTGGGCTTTGAACAATTCGACGTGGTCAGAGTGCCCTTCCCGTTCACGGATCGTACTGCTACTAAAAACAGACCTGCACT
GGTTCTCTCTCAATCCGTCTTTAGTAATGCAGCAGACCATTCAGTGCTTGTGATGGTCACCTCGGCGATGAATGATTGGC
CTTTGGACTGCCCCATAAAAGACCTGCAAGCCGCAGGTTTGCCAGCACCCTCAAGAATCCGCTTCAAACTCTTCACGCTC
GACAACAGACTGATACGAGGAAAGATTGGTGCACTTTCCGCCGCTGATAGACAAGCATTCAAAAAGCAATTTGATCGATT
GGTCGCAACAAGCTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8480.50 Da Isoelectric Point: 4.1954
>AT35382 WP_162050317.1 NZ_AP022345:c1260798-1260568 [Fluviibacter phosphoraccumulans]
MPAIAKITSKGQTTIPAEVRESLNFNPGDLLEWEVNADGSARVRRIQPLDLEYMRAVEGTLTEWGCAEDEEAYRGL
MPAIAKITSKGQTTIPAEVRESLNFNPGDLLEWEVNADGSARVRRIQPLDLEYMRAVEGTLTEWGCAEDEEAYRGL
Download Length: 231 bp
>AT35382 NZ_AP022345:c1260798-1260568 [Fluviibacter phosphoraccumulans]
ATGCCAGCTATCGCCAAAATCACCTCAAAAGGCCAAACTACCATTCCAGCAGAGGTCAGAGAGTCGCTTAACTTTAATCC
GGGCGATTTGCTGGAATGGGAAGTGAATGCAGACGGTTCAGCCAGAGTGCGGCGTATTCAACCACTAGACCTAGAGTACA
TGCGCGCCGTTGAAGGCACGCTCACCGAATGGGGCTGCGCGGAAGACGAAGAGGCGTATCGTGGGCTTTGA
ATGCCAGCTATCGCCAAAATCACCTCAAAAGGCCAAACTACCATTCCAGCAGAGGTCAGAGAGTCGCTTAACTTTAATCC
GGGCGATTTGCTGGAATGGGAAGTGAATGCAGACGGTTCAGCCAGAGTGCGGCGTATTCAACCACTAGACCTAGAGTACA
TGCGCGCCGTTGAAGGCACGCTCACCGAATGGGGCTGCGCGGAAGACGAAGAGGCGTATCGTGGGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|