Detailed information of TA system TA035379

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 328509..329070
• Replicon: chromosome
• Accession: NZ_AP022345
• Organism: Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ICHIAU1_RS01660
• Protein ID: WP_162049012.1
• Coordinates: 328765..329070 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ICHIAU1_RS01655
• Protein ID: WP_162049013.1
• Coordinates: 328509..328760 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIAU1_RS01630	323779..324210	+	432	WP_162049017.1	transcriptional regulator	-
ICHIAU1_RS01635	324362..325666	+	1305	WP_162049016.1	dNTP triphosphohydrolase	-
ICHIAU1_RS01640	325663..326229	+	567	WP_202930727.1	hypothetical protein	-
ICHIAU1_RS01645	326411..327001	-	591	WP_162049015.1	GNAT family N-acetyltransferase	-
ICHIAU1_RS01650	327458..328156	+	699	WP_162049014.1	toll/interleukin-1 receptor domain-containing protein	-
ICHIAU1_RS01655	328509..328760	+	252	WP_162049013.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ICHIAU1_RS01660	328765..329070	+	306	WP_162049012.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ICHIAU1_RS01665	329141..329383	+	243	WP_162049011.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIAU1_RS01670	329674..331020	+	1347	WP_162049010.1	type II toxin-antitoxin system HipA family toxin YjjJ	-
ICHIAU1_RS01675	331081..331356	+	276	WP_162049009.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIAU1_RS01680	331353..331694	+	342	WP_162049008.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ICHIAU1_RS01685	331680..332738	-	1059	WP_162049007.1	glycosyltransferase family 9 protein	-
ICHIAU1_RS01690	332779..333819	+	1041	WP_162049006.1	glycosyltransferase family 9 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-70)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11449.62 Da
• Isoelectric Point: 10.2841

>T35379 WP_162049012.1 NZ_AP022345:328765-329070 [Fluviibacter phosphoraccumulans]
VAYRLQFLPEALKEWEALDGSIKAPLRAALKKRLENPHVPSAVLGSELAGCYKIKLRKQGYRLVYVVEDDVLVVIVLAIG
KRERLATYEYALKRLITKRVG

Nucleotide

• Length: 306 bp

>T35379 NZ_AP022345:328765-329070 [Fluviibacter phosphoraccumulans]
GTGGCTTACCGCCTGCAGTTTCTGCCCGAGGCTTTGAAAGAGTGGGAGGCGCTCGATGGCAGTATCAAAGCGCCACTCCG
AGCTGCCCTGAAAAAACGGCTGGAGAATCCACACGTCCCGAGTGCGGTGCTTGGATCAGAACTTGCTGGTTGCTACAAAA
TCAAACTTCGCAAGCAAGGGTATCGCCTCGTCTACGTGGTTGAAGATGATGTTCTAGTAGTAATTGTGCTGGCCATCGGC
AAACGAGAGCGGCTGGCTACTTACGAGTATGCCCTTAAGCGGTTGATAACGAAGCGGGTTGGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9397.70 Da
• Isoelectric Point: 4.7335

>AT35379 WP_162049013.1 NZ_AP022345:328509-328760 [Fluviibacter phosphoraccumulans]
MDTIYADYSVSMSEFKKNPAQVLRTAGEKPVAVLSHNRPAFYMVTPQLFESLVEELADHDLIDIVRDRLTRKTTAVDVDI
NSI

Nucleotide

• Length: 252 bp

>AT35379 NZ_AP022345:328509-328760 [Fluviibacter phosphoraccumulans]
ATGGATACCATTTACGCAGATTACTCAGTGAGCATGTCCGAGTTCAAGAAGAACCCGGCTCAAGTGCTGCGCACCGCAGG
TGAAAAGCCCGTGGCAGTTTTGAGCCATAACCGCCCTGCTTTTTACATGGTGACGCCACAGCTATTTGAATCTCTGGTTG
AAGAGCTGGCTGATCACGATTTGATCGACATCGTTCGAGATCGCTTAACGCGCAAAACCACAGCCGTCGACGTCGACATC
AACAGTATTTAA