Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 271071..271557 Replicon chromosome
Accession NZ_AP022345
Organism Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag ICHIAU1_RS01365 Protein ID WP_162049066.1
Coordinates 271071..271346 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag ICHIAU1_RS01370 Protein ID WP_162049065.1
Coordinates 271330..271557 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIAU1_RS01335 266151..266441 - 291 WP_162049071.1 co-chaperone GroES -
ICHIAU1_RS01340 266678..268060 + 1383 WP_162049070.1 Fic family protein -
ICHIAU1_RS01345 268115..269263 - 1149 WP_162049069.1 Fic family protein -
ICHIAU1_RS01350 269415..269717 + 303 WP_202930719.1 helix-turn-helix domain-containing protein -
ICHIAU1_RS01355 269686..270432 - 747 WP_162049068.1 autoinducer binding domain-containing protein -
ICHIAU1_RS01360 270566..271054 + 489 WP_162049067.1 hypothetical protein -
ICHIAU1_RS01365 271071..271346 - 276 WP_162049066.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ICHIAU1_RS01370 271330..271557 - 228 WP_162049065.1 ribbon-helix-helix protein, CopG family Antitoxin
ICHIAU1_RS01375 271698..271976 - 279 WP_162049064.1 plasmid stabilization protein -
ICHIAU1_RS01380 271973..272230 - 258 WP_162049063.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
ICHIAU1_RS01385 272325..273074 + 750 WP_162049062.1 YdcF family protein -
ICHIAU1_RS01390 273116..273973 - 858 WP_162049061.1 hypothetical protein -
ICHIAU1_RS01395 273982..275403 - 1422 WP_202930720.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-35)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10601.41 Da        Isoelectric Point: 10.2349

>T35375 WP_162049066.1 NZ_AP022345:c271346-271071 [Fluviibacter phosphoraccumulans]
MPWIIKYTESAQRQLKKLDKAAALRVLDYMDERIGILADPRSAGKNLVGPRMGSYWRYRVGDLRVICDIQDQTVVILVIE
IGHRREVYRGR

Download         Length: 276 bp

>T35375 NZ_AP022345:c271346-271071 [Fluviibacter phosphoraccumulans]
TTGCCATGGATCATTAAATATACCGAGTCTGCGCAGCGGCAGCTTAAGAAGCTGGACAAGGCGGCTGCGCTGCGGGTCCT
CGATTATATGGATGAGCGGATCGGTATTCTGGCTGACCCGAGAAGCGCAGGTAAAAATCTAGTTGGGCCACGGATGGGTT
CATATTGGCGGTATCGGGTTGGGGATCTGCGGGTGATCTGCGATATTCAGGATCAAACCGTTGTTATTCTGGTCATTGAG
ATCGGCCATCGGCGAGAGGTGTATCGGGGGCGGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8464.55 Da        Isoelectric Point: 4.5084

>AT35375 WP_162049065.1 NZ_AP022345:c271557-271330 [Fluviibacter phosphoraccumulans]
MAVSLRLDPEIEQRLDHLAAQTGRAKSYYLRELIEGGLDDLEGFYLADATMERVRKGEESVLDAAEVRKSIAMDH

Download         Length: 228 bp

>AT35375 NZ_AP022345:c271557-271330 [Fluviibacter phosphoraccumulans]
ATGGCGGTGTCGCTCAGGCTGGACCCTGAAATTGAACAACGGCTCGATCATTTGGCGGCCCAGACCGGGCGTGCCAAGTC
TTACTATTTACGCGAGCTGATCGAGGGTGGCCTCGATGATCTAGAAGGTTTTTACCTGGCGGATGCCACGATGGAGCGTG
TTCGCAAAGGTGAGGAGTCTGTGCTGGATGCGGCTGAAGTAAGGAAGTCGATTGCCATGGATCATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References