Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1869055..1869722 Replicon chromosome
Accession NZ_AP022332
Organism Methylosinus sp. C49 isolate Methylosinus sp. C49

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GYH34_RS09030 Protein ID WP_161913291.1
Coordinates 1869055..1869474 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GYH34_RS09035 Protein ID WP_108917441.1
Coordinates 1869471..1869722 (-) Length 84 a.a.

Genomic Context

GYH34_RS09025GYH34_RS09015GYH34_RS09020GYH34_RS09030GYH34_RS09035GYH34_RS09040GYH34_RS09045GYH34_RS09050GYH34_RS09055
Location: 1865860..1869000 (3141 bp)
Type: Others
Protein ID: WP_161913290.1
Location: 1864540..1865091 (552 bp)
Type: Others
Protein ID: WP_161913288.1
Location: 1865098..1865721 (624 bp)
Type: Others
Protein ID: WP_161913289.1
Location: 1869055..1869474 (420 bp)
Type: Toxin
Protein ID: WP_161913291.1
Location: 1869471..1869722 (252 bp)
Type: Antitoxin
Protein ID: WP_108917441.1
Location: 1869788..1871248 (1461 bp)
Type: Others
Protein ID: WP_161914954.1
Location: 1871333..1872016 (684 bp)
Type: Others
Protein ID: WP_018266270.1
Location: 1872330..1872605 (276 bp)
Type: Others
Protein ID: WP_024880626.1
Location: 1872984..1874402 (1419 bp)
Type: Others
Protein ID: WP_161913292.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GYH34_RS090151864540..1865091-552WP_161913288.1Uma2 family endonuclease-
GYH34_RS090201865098..1865721-624WP_161913289.1DUF938 domain-containing protein-
GYH34_RS090251865860..1869000+3141WP_161913290.1autotransporter domain-containing protein-
GYH34_RS090301869055..1869474-420WP_161913291.1type II toxin-antitoxin system VapC family toxinToxin
GYH34_RS090351869471..1869722-252WP_108917441.1toxin-antitoxin systemAntitoxin
GYH34_RS090401869788..1871248-1461WP_161914954.1amidophosphoribosyltransferase-
GYH34_RS090451871333..1872016-684WP_018266270.1CvpA family protein-
GYH34_RS090501872330..1872605-276WP_024880626.1hypothetical protein-
GYH34_RS090551872984..1874402-1419WP_161913292.1DNA repair protein RadA-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15518.81 Da        Isoelectric Point: 8.9608

>T35366 WP_161913291.1 NZ_AP022332:c1869474-1869055 [Methylosinus sp. C49]
MILLDTNVVSELVKARPHPLVLAWLDRHPFSSVWISTISVMELRFGLELLDPSRRKAELAAALARLTESTFGDRIAPFDL
KAAEAAGRLAAARRRNGTTVDHRDTQIAGIALAHRARLVTRNLRDFADLDVEVTNPWNE

Download         Length: 420 bp

>T35366 NZ_AP022332:c1869474-1869055 [Methylosinus sp. C49]
TTGATTCTGCTCGACACGAATGTCGTCTCGGAACTCGTGAAAGCGAGACCGCATCCATTGGTCCTGGCGTGGCTCGATCG
CCATCCTTTCTCTTCGGTCTGGATATCAACTATTTCCGTGATGGAGCTGCGCTTTGGCTTGGAGCTTCTCGACCCGAGCC
GCAGGAAGGCGGAACTCGCCGCTGCGCTCGCCCGGCTGACGGAATCGACATTCGGCGACCGCATAGCGCCTTTCGACTTG
AAGGCCGCCGAGGCGGCCGGCCGGCTCGCGGCCGCACGCCGCCGCAATGGAACGACCGTCGACCACCGCGACACACAGAT
CGCCGGCATTGCTCTCGCCCATCGCGCGCGGCTCGTGACACGCAATCTGCGCGATTTCGCCGATCTCGATGTCGAGGTGA
CGAATCCTTGGAATGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9333.27 Da        Isoelectric Point: 4.5593

>AT35366 WP_108917441.1 NZ_AP022332:c1869722-1869471 [Methylosinus sp. C49]
MAQLLVRNLADDVKQKLRRRASEHGRSMEEEARRIIEAAVGGQGAEDYGWASRLSAQFSEFGFSDDEASVFELREAARPA
EFD

Download         Length: 252 bp

>AT35366 NZ_AP022332:c1869722-1869471 [Methylosinus sp. C49]
ATGGCTCAGCTGCTCGTACGCAATCTCGCCGACGACGTGAAGCAAAAGCTTCGGCGCCGAGCGTCGGAGCATGGGCGCAG
CATGGAGGAAGAGGCGCGCCGCATCATAGAGGCGGCAGTCGGCGGCCAAGGGGCCGAAGACTATGGATGGGCCTCTCGCC
TCTCTGCGCAATTCTCCGAATTCGGCTTCTCCGATGACGAGGCGAGCGTTTTTGAGCTCCGCGAAGCGGCGCGGCCGGCC
GAATTCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References