Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1503637..1504447 Replicon chromosome
Accession NZ_AP022332
Organism Methylosinus sp. C49 isolate Methylosinus sp. C49

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag GYH34_RS07135 Protein ID WP_161912962.1
Coordinates 1503637..1504164 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag GYH34_RS07140 Protein ID WP_161912963.1
Coordinates 1504157..1504447 (-) Length 97 a.a.

Genomic Context

GYH34_RS07115GYH34_RS07125GYH34_RS07130GYH34_RS07120GYH34_RS07135GYH34_RS07140GYH34_RS07145GYH34_RS07150GYH34_RS07155GYH34_RS07160GYH34_RS07165GYH34_RS07170
Location: 1498793..1499791 (999 bp)
Type: Others
Protein ID: WP_161912959.1
Location: 1500802..1501506 (705 bp)
Type: Others
Protein ID: WP_064033743.1
Location: 1501720..1503627 (1908 bp)
Type: Others
Protein ID: WP_161912961.1
Location: 1499876..1500655 (780 bp)
Type: Others
Protein ID: WP_161912960.1
Location: 1503637..1504164 (528 bp)
Type: Toxin
Protein ID: WP_161912962.1
Location: 1504157..1504447 (291 bp)
Type: Antitoxin
Protein ID: WP_161912963.1
Location: 1504497..1505291 (795 bp)
Type: Others
Protein ID: WP_161912964.1
Location: 1505288..1506205 (918 bp)
Type: Others
Protein ID: WP_161912965.1
Location: 1506202..1507260 (1059 bp)
Type: Others
Protein ID: WP_161912966.1
Location: 1507316..1508026 (711 bp)
Type: Others
Protein ID: WP_161912967.1
Location: 1508008..1508475 (468 bp)
Type: Others
Protein ID: WP_161912968.1
Location: 1508513..1509289 (777 bp)
Type: Others
Protein ID: WP_161912969.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GYH34_RS071151498793..1499791+999WP_161912959.1LLM class flavin-dependent oxidoreductase-
GYH34_RS071201499876..1500655-780WP_161912960.1hypothetical protein-
GYH34_RS071251500802..1501506+705WP_064033743.1transcriptional repressor LexA-
GYH34_RS071301501720..1503627+1908WP_161912961.1AsmA family protein-
GYH34_RS071351503637..1504164-528WP_161912962.1GNAT family N-acetyltransferaseToxin
GYH34_RS071401504157..1504447-291WP_161912963.1DUF1778 domain-containing proteinAntitoxin
GYH34_RS071451504497..1505291-795WP_161912964.1ABC transporter permease subunit-
GYH34_RS071501505288..1506205-918WP_161912965.1ABC transporter permease subunit-
GYH34_RS071551506202..1507260-1059WP_161912966.1ABC transporter ATP-binding protein-
GYH34_RS071601507316..1508026-711WP_161912967.1class I SAM-dependent methyltransferase-
GYH34_RS071651508008..1508475-468WP_161912968.1DNA polymerase III subunit chi-
GYH34_RS071701508513..1509289-777WP_161912969.1exodeoxyribonuclease III-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(34-152)

Antitoxin

Vibrio phage ICP1, Orf50

(12-89)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19219.28 Da        Isoelectric Point: 9.7099

>T35365 WP_161912962.1 NZ_AP022332:c1504164-1503637 [Methylosinus sp. C49]
MAETPPSLEPPAPLSESHELAEFRSGETVLDEWLMRRALANMEAGASKTYVLCAAGSQQVVGFYALSMGQILDREALGSM
RRNMPRHIPSVILGRLAIDARCQGRGIGRALLHDAVSRSRRAAREVAARLLVVHAISPTAEAFYRHHGFMRLPVETPTLA
LDLVKLERVIGKERG

Download         Length: 528 bp

>T35365 NZ_AP022332:c1504164-1503637 [Methylosinus sp. C49]
ATGGCTGAAACGCCGCCGTCTCTCGAGCCGCCCGCGCCACTGAGCGAAAGCCATGAGCTCGCAGAATTTCGCAGCGGCGA
AACCGTTCTGGACGAATGGCTGATGAGGCGCGCCCTCGCCAATATGGAGGCCGGCGCGAGCAAGACCTATGTGCTGTGCG
CCGCCGGCTCGCAACAGGTCGTCGGCTTCTATGCGCTGAGCATGGGCCAGATTCTCGATCGGGAAGCGCTCGGCTCCATG
CGGCGAAACATGCCGCGACATATTCCTTCGGTGATCCTCGGGCGGCTCGCCATAGACGCGCGCTGTCAGGGACGCGGCAT
AGGCAGAGCGCTGCTTCACGACGCCGTTTCACGCTCGCGGCGCGCCGCGCGCGAAGTGGCCGCCCGCCTCCTCGTCGTGC
ACGCGATCTCGCCGACGGCGGAGGCCTTCTACCGCCATCATGGCTTCATGCGCCTGCCGGTGGAAACGCCGACGCTGGCG
CTCGATCTCGTGAAGCTCGAAAGGGTGATCGGAAAAGAGAGAGGCTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10744.25 Da        Isoelectric Point: 10.2844

>AT35365 WP_161912963.1 NZ_AP022332:c1504447-1504157 [Methylosinus sp. C49]
MKPAPPLAEVNIHLRAREQDRSLIDQAAELTGTNRSQFMLASALSAAKNVLLDQTTIVADRRAFRKILDWMDAPASDEEE
AGMKRLAARRAQWRNG

Download         Length: 291 bp

>AT35365 NZ_AP022332:c1504447-1504157 [Methylosinus sp. C49]
ATGAAACCCGCGCCGCCGCTCGCCGAAGTCAATATTCACCTGCGCGCCCGCGAGCAGGACCGCTCGCTCATCGACCAGGC
GGCCGAATTGACGGGAACCAATCGCTCGCAATTCATGCTCGCCTCCGCCTTGAGCGCGGCGAAGAATGTCCTGCTCGATC
AGACGACCATCGTGGCGGACCGGCGAGCCTTTCGAAAAATTCTCGATTGGATGGACGCCCCGGCTTCCGACGAGGAAGAA
GCAGGCATGAAGCGGCTCGCCGCGCGCAGAGCCCAATGGCGGAATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References