Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 248099..248627 Replicon chromosome
Accession NZ_AP022332
Organism Methylosinus sp. C49 isolate Methylosinus sp. C49

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GYH34_RS01170 Protein ID WP_161911995.1
Coordinates 248099..248380 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag GYH34_RS01175 Protein ID WP_161911996.1
Coordinates 248367..248627 (-) Length 87 a.a.

Genomic Context

GYH34_RS01145GYH34_RS01150GYH34_RS01155GYH34_RS01160GYH34_RS01165GYH34_RS01195GYH34_RS01200GYH34_RS01170GYH34_RS01175GYH34_RS01180GYH34_RS01185GYH34_RS01190GYH34_RS01205GYH34_RS01210
Location: 243468..244175 (708 bp)
Type: Others
Protein ID: WP_161911991.1
Location: 244187..244960 (774 bp)
Type: Others
Protein ID: WP_161911992.1
Location: 245231..245977 (747 bp)
Type: Others
Protein ID: WP_161911993.1
Location: 245978..246922 (945 bp)
Type: Others
Protein ID: WP_161911994.1
Location: 247172..248053 (882 bp)
Type: Others
Protein ID: WP_018267072.1
Location: 251568..251798 (231 bp)
Type: Others
Protein ID: WP_161912000.1
Location: 251785..252105 (321 bp)
Type: Others
Protein ID: WP_161912001.1
Location: 248099..248380 (282 bp)
Type: Toxin
Protein ID: WP_161911995.1
Location: 248367..248627 (261 bp)
Type: Antitoxin
Protein ID: WP_161911996.1
Location: 248679..249308 (630 bp)
Type: Others
Protein ID: WP_161911997.1
Location: 249310..250245 (936 bp)
Type: Others
Protein ID: WP_161911998.1
Location: 250346..251236 (891 bp)
Type: Others
Protein ID: WP_161911999.1
Location: 252113..252556 (444 bp)
Type: Others
Protein ID: WP_161912002.1
Location: 252581..253612 (1032 bp)
Type: Others
Protein ID: WP_161912003.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GYH34_RS01145243468..244175+708WP_161911991.1rhomboid family intramembrane serine protease-
GYH34_RS01150244187..244960+774WP_161911992.1hypothetical protein-
GYH34_RS01155245231..245977+747WP_161911993.1electron transfer flavoprotein subunit beta/FixA family protein-
GYH34_RS01160245978..246922+945WP_161911994.1FAD-binding protein-
GYH34_RS01165247172..248053+882WP_018267072.13-hydroxybutyryl-CoA dehydrogenase-
GYH34_RS01170248099..248380-282WP_161911995.1type II toxin-antitoxin system YafQ family toxinToxin
GYH34_RS01175248367..248627-261WP_161911996.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
GYH34_RS01180248679..249308-630WP_161911997.1protein-methionine-sulfoxide reductase heme-binding subunit MsrQ-
GYH34_RS01185249310..250245-936WP_161911998.1protein-methionine-sulfoxide reductase catalytic subunit MsrP-
GYH34_RS01190250346..251236-891WP_161911999.1RNA polymerase sigma factor RpoH-
GYH34_RS01195251568..251798+231WP_161912000.1NAD(P)H-dependent oxidoreductase-
GYH34_RS01200251785..252105+321WP_161912001.1type II toxin-antitoxin system PemK/MazF family toxin-
GYH34_RS01205252113..252556-444WP_161912002.1DUF2267 domain-containing protein-
GYH34_RS01210252581..253612-1032WP_161912003.1RluA family pseudouridine synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-77)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10980.64 Da        Isoelectric Point: 8.5096

>T35363 WP_161911995.1 NZ_AP022332:c248380-248099 [Methylosinus sp. C49]
MRAIKYTSRFRHDYRRERSGVLGKKIDQLLLDAVNLLAADQPLPARYCDHELIGEWKDHRDCHLRPDLLLIYRKPDAERL
ELVRLGSHSELGF

Download         Length: 282 bp

>T35363 NZ_AP022332:c248380-248099 [Methylosinus sp. C49]
ATGCGGGCGATTAAATACACCTCGCGCTTCCGGCACGATTATCGGCGTGAACGGTCAGGGGTGCTGGGCAAGAAAATCGA
TCAGCTGCTTTTGGACGCCGTCAACCTTCTGGCGGCAGATCAGCCGTTGCCAGCGCGATATTGCGACCATGAATTGATCG
GGGAATGGAAGGATCACAGAGATTGCCACCTTCGCCCCGACCTATTGCTCATATACCGCAAGCCTGACGCTGAAAGGCTG
GAATTGGTGCGCCTCGGCTCACACAGCGAGCTCGGATTCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9276.71 Da        Isoelectric Point: 4.5680

>AT35363 WP_161911996.1 NZ_AP022332:c248627-248367 [Methylosinus sp. C49]
MTNTVVRARIDEHVKEEAAAVLATIGLTVSDAFRLMMVRIATDKTLPFELLVPNAETVEAMKAARRGELVDVGAPENLLQ
SLNAGD

Download         Length: 261 bp

>AT35363 NZ_AP022332:c248627-248367 [Methylosinus sp. C49]
ATGACCAACACCGTCGTCCGTGCGCGCATCGACGAGCATGTGAAAGAGGAAGCCGCCGCCGTGCTGGCGACCATCGGCCT
GACTGTGTCCGATGCGTTCCGGCTCATGATGGTTCGGATCGCGACGGACAAGACCTTGCCGTTCGAGCTGCTCGTGCCGA
ACGCTGAAACGGTCGAGGCTATGAAGGCCGCTCGCCGTGGTGAGCTCGTCGATGTCGGCGCCCCTGAAAACCTGCTCCAG
AGCCTGAATGCGGGCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References