Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2064302..2064939 Replicon chromosome
Accession NZ_AP022322
Organism Veillonella sp. S12025-13

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KJS32_RS09555 Protein ID WP_244856264.1
Coordinates 2064538..2064939 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID E4LD34
Locus tag KJS32_RS09550 Protein ID WP_009351573.1
Coordinates 2064302..2064532 (+) Length 77 a.a.

Genomic Context

KJS32_RS09540KJS32_RS09550KJS32_RS09555KJS32_RS09545KJS32_RS09560KJS32_RS09565KJS32_RS09570
Location: 2061787..2062644 (858 bp)
Type: Others
Protein ID: WP_082717874.1
Location: 2064302..2064532 (231 bp)
Type: Antitoxin
Protein ID: WP_009351573.1
Location: 2064538..2064939 (402 bp)
Type: Toxin
Protein ID: WP_244856264.1
Location: 2062740..2063492 (753 bp)
Type: Others
Protein ID: WP_213467427.1
Location: 2065023..2066894 (1872 bp)
Type: Others
Protein ID: WP_213467429.1
Location: 2067260..2068645 (1386 bp)
Type: Others
Protein ID: WP_213467430.1
Location: 2068833..2069630 (798 bp)
Type: Others
Protein ID: WP_213467431.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KJS32_RS09540 (VEIS1202513_18730)2061787..2062644+858WP_082717874.1methylenetetrahydrofolate reductase-
KJS32_RS09545 (VEIS1202513_18740)2062740..2063492-753WP_213467427.116S rRNA (guanine(527)-N(7))-methyltransferase RsmG-
KJS32_RS09550 (VEIS1202513_18750)2064302..2064532+231WP_009351573.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
KJS32_RS09555 (VEIS1202513_18760)2064538..2064939+402WP_244856264.1type II toxin-antitoxin system VapC family toxinToxin
KJS32_RS09560 (VEIS1202513_18770)2065023..2066894-1872WP_213467429.1tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG-
KJS32_RS09565 (VEIS1202513_18790)2067260..2068645-1386WP_213467430.1tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE-
KJS32_RS09570 (VEIS1202513_18800)2068833..2069630-798WP_213467431.1RNA-binding cell elongation regulator Jag/EloR-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-121)

Antitoxin

SpoVT-AbrB domain

(9-44)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14955.30 Da        Isoelectric Point: 6.6378

>T35320 WP_244856264.1 NZ_AP022322:2064538-2064939 [Veillonella sp. S12025-13]
MLDTNICIYAIKQEPEVVLQKILKHHPSDICISSITYAELMHGVEKSQSKDKNRLALTLLLSPIQIIDFDSHAAEEYGKI
KADLQSQGKVIGPMDLLIASHAKSKDLTIVTNNTKEFKRVNQLEVEDWSKPLS

Download         Length: 402 bp

>T35320 NZ_AP022322:2064538-2064939 [Veillonella sp. S12025-13]
ATGTTAGATACTAATATATGTATTTATGCTATCAAACAAGAGCCAGAAGTTGTACTACAGAAAATATTGAAACATCATCC
TTCAGATATATGTATTTCATCAATTACATATGCTGAACTAATGCATGGTGTAGAAAAAAGCCAATCAAAAGATAAAAATA
GATTAGCTTTAACACTTTTATTATCACCTATACAAATTATTGATTTTGACAGCCACGCTGCTGAGGAATATGGAAAAATA
AAAGCCGATTTACAATCACAAGGAAAAGTTATTGGTCCTATGGATCTACTCATTGCAAGCCACGCAAAGTCAAAGGATCT
TACCATTGTTACTAATAATACAAAAGAGTTTAAAAGAGTAAATCAATTAGAAGTTGAAGATTGGTCTAAACCATTAAGCT
AA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8690.84 Da        Isoelectric Point: 4.4217

>AT35320 WP_009351573.1 NZ_AP022322:2064302-2064532 [Veillonella sp. S12025-13]
MTTAKLFENGRSQAVRLPKEFRFNGDEVIINKIGNVVLLMPKDDEWAGFVAGLSLFTDDFMCNGREDIDHQERETL

Download         Length: 231 bp

>AT35320 NZ_AP022322:2064302-2064532 [Veillonella sp. S12025-13]
ATGACCACAGCAAAGCTATTTGAAAATGGCCGTAGCCAGGCTGTACGATTACCAAAGGAATTTCGATTTAATGGTGATGA
AGTAATCATCAACAAAATAGGAAATGTAGTCTTACTTATGCCAAAAGATGATGAATGGGCAGGATTTGTAGCTGGTTTAT
CATTATTTACAGATGATTTTATGTGTAACGGACGGGAAGATATTGATCATCAGGAGCGTGAAACCTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBE4LD34

References