Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 423041..423518 Replicon chromosome
Accession NZ_AP022322
Organism Veillonella sp. S12025-13

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KJS32_RS01855 Protein ID WP_024064148.1
Coordinates 423252..423518 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E4LDZ1
Locus tag KJS32_RS01850 Protein ID WP_009352129.1
Coordinates 423041..423262 (+) Length 74 a.a.

Genomic Context


KJS32_RS01830KJS32_RS01835KJS32_RS01840KJS32_RS01845KJS32_RS01850KJS32_RS01855KJS32_RS01860KJS32_RS01865KJS32_RS01875KJS32_RS01880KJS32_RS01870
Location: 419281..420171 (891 bp)
Type: Others
Protein ID: WP_024064152.1
Location: 420214..421110 (897 bp)
Type: Others
Protein ID: WP_213467685.1
Location: 421097..421915 (819 bp)
Type: Others
Protein ID: WP_213467686.1
Location: 421915..422658 (744 bp)
Type: Others
Protein ID: WP_213467687.1
Location: 423041..423262 (222 bp)
Type: Antitoxin
Protein ID: WP_009352129.1
Location: 423252..423518 (267 bp)
Type: Toxin
Protein ID: WP_024064148.1
Location: 423529..423741 (213 bp)
Type: Others
Protein ID: WP_024064147.1
Location: 423808..424893 (1086 bp)
Type: Others
Protein ID: WP_024064146.1
Location: 426019..426822 (804 bp)
Type: Others
Protein ID: WP_213467689.1
Location: 426834..427772 (939 bp)
Type: Others
Protein ID: WP_213467690.1
Location: 424987..425778 (792 bp)
Type: Others
Protein ID: WP_213467688.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KJS32_RS01830 (VEIS1202513_03660)419281..420171+891WP_024064152.1phosphate ABC transporter substrate-binding protein-
KJS32_RS01835 (VEIS1202513_03670)420214..421110+897WP_213467685.1phosphate ABC transporter permease subunit PstC-
KJS32_RS01840 (VEIS1202513_03680)421097..421915+819WP_213467686.1ABC transporter permease subunit-
KJS32_RS01845 (VEIS1202513_03690)421915..422658+744WP_213467687.1ATP-binding cassette domain-containing protein-
KJS32_RS01850 (VEIS1202513_03700)423041..423262+222WP_009352129.1DUF6290 family proteinAntitoxin
KJS32_RS01855 (VEIS1202513_03710)423252..423518+267WP_024064148.1type II toxin-antitoxin system RelE/ParE family toxinToxin
KJS32_RS01860 (VEIS1202513_03720)423529..423741+213WP_024064147.1hypothetical protein-
KJS32_RS01865 (VEIS1202513_03730)423808..424893+1086WP_024064146.1hypothetical protein-
KJS32_RS01870 (VEIS1202513_03740)424987..425778-792WP_213467688.1carbon-nitrogen family hydrolase-
KJS32_RS01875 (VEIS1202513_03750)426019..426822+804WP_213467689.1polysaccharide deacetylase family protein-
KJS32_RS01880 (VEIS1202513_03760)426834..427772+939WP_213467690.1phosphodiester glycosidase family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10595.25 Da        Isoelectric Point: 10.2849

>T35319 WP_024064148.1 NZ_AP022322:423252-423518 [Veillonella sp. S12025-13]
MAYKLEFSKRFDKQFSKLDKSMQRYLFNWLIKNIDNVENPRYSGKSLTGNKTGLWRYRIGNYRVIADINDDRCIILALEV
GHRKEIYK

Download         Length: 267 bp

>T35319 NZ_AP022322:423252-423518 [Veillonella sp. S12025-13]
ATGGCTTATAAACTTGAATTTTCTAAAAGGTTTGACAAGCAATTTTCTAAATTAGATAAATCAATGCAACGCTATCTTTT
TAATTGGCTCATAAAAAATATAGATAATGTAGAAAACCCTAGGTACTCAGGCAAATCATTGACGGGGAATAAAACAGGGC
TGTGGCGTTATCGCATTGGTAATTATAGAGTCATAGCTGATATTAATGATGATAGATGTATTATTTTAGCGTTAGAAGTG
GGTCATCGAAAAGAAATTTACAAATAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8500.65 Da        Isoelectric Point: 4.1835

>AT35319 WP_009352129.1 NZ_AP022322:423041-423262 [Veillonella sp. S12025-13]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYEQDPVTYSVAEMRAKYGL

Download         Length: 222 bp

>AT35319 NZ_AP022322:423041-423262 [Veillonella sp. S12025-13]
ATGGCAAATATTTCAGTCCGTTTAAATGAACAAGAAGAAGAGTTATTTAAAACCTATGCTGAGTTTATGGATGAAACACT
TTCTACCCTCTTTAAGAAGGCTTTACTAGAAAAGATTGAAGACGAATTTGATCTTAAGGTAGGTCAAAAAGCATTAGCAG
AATACGAGCAAGATCCAGTTACCTATTCTGTAGCGGAAATGCGTGCAAAATATGGCTTATAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7YYS4

References