Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2089222..2089859 Replicon chromosome
Accession NZ_AP022321
Organism Veillonella nakazawae strain T1-7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag VEIT17_RS09750 Protein ID WP_178885953.1
Coordinates 2089449..2089859 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag VEIT17_RS09745 Protein ID WP_178885951.1
Coordinates 2089222..2089452 (+) Length 77 a.a.

Genomic Context

VEIT17_RS09730VEIT17_RS09745VEIT17_RS09750VEIT17_RS09735VEIT17_RS09740VEIT17_RS09755VEIT17_RS09760VEIT17_RS09765
Location: 2086057..2086914 (858 bp)
Type: Others
Protein ID: WP_082717874.1
Location: 2089222..2089452 (231 bp)
Type: Antitoxin
Protein ID: WP_178885951.1
Location: 2089449..2089859 (411 bp)
Type: Toxin
Protein ID: WP_178885953.1
Location: 2087088..2087552 (465 bp)
Type: Others
Protein ID: WP_038125930.1
Location: 2087790..2088542 (753 bp)
Type: Others
Protein ID: WP_178885949.1
Location: 2089943..2091814 (1872 bp)
Type: Others
Protein ID: WP_178885955.1
Location: 2092193..2093578 (1386 bp)
Type: Others
Protein ID: WP_178885957.1
Location: 2093766..2094563 (798 bp)
Type: Others
Protein ID: WP_178885959.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIT17_RS097302086057..2086914+858WP_082717874.1methylenetetrahydrofolate reductase-
VEIT17_RS097352087088..2087552-465WP_038125930.1IS200/IS605 family transposase-
VEIT17_RS097402087790..2088542-753WP_178885949.116S rRNA (guanine(527)-N(7))-methyltransferase RsmG-
VEIT17_RS097452089222..2089452+231WP_178885951.1antitoxinAntitoxin
VEIT17_RS097502089449..2089859+411WP_178885953.1type II toxin-antitoxin system VapC family toxinToxin
VEIT17_RS097552089943..2091814-1872WP_178885955.1tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG-
VEIT17_RS097602092193..2093578-1386WP_178885957.1tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE-
VEIT17_RS097652093766..2094563-798WP_178885959.1protein jag-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--2087088..2087552464


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

SpoVT-AbrB domain

(9-44)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15305.77 Da        Isoelectric Point: 7.3820

>T35318 WP_178885953.1 NZ_AP022321:2089449-2089859 [Veillonella nakazawae]
MKYMLDTNICIYAIKQEPEVVLQKILKHHPSDICISSITYAELMHGVEKSQSKDKNRLALTLLLSPIQIVDFDSHAAEEY
GKIKADLQSQGKVIGPMDLLIASHAKSKGLTIVTNNTKEFKRVNQLEVEDWSKPLS

Download         Length: 411 bp

>T35318 NZ_AP022321:2089449-2089859 [Veillonella nakazawae]
ATGAAGTATATGTTAGATACTAATATATGTATTTATGCTATCAAACAAGAGCCAGAAGTTGTACTACAAAAAATTTTAAA
GCATCATCCTTCAGATATCTGTATATCATCAATTACATATGCTGAGTTAATGCATGGTGTAGAAAAAAGTCAATCAAAAG
ATAAAAATAGATTAGCTTTAACACTTTTATTATCACCTATCCAAATTGTTGATTTTGACAGCCACGCTGCTGAGGAATAT
GGAAAAATAAAAGCCGATTTACAATCACAAGGAAAAGTTATTGGTCCTATGGATCTACTCATTGCAAGCCACGCAAAGTC
AAAGGGTCTTACCATTGTTACTAATAATACAAAAGAGTTTAAAAGAGTAAATCAATTAGAAGTTGAAGATTGGTCTAAAC
CATTAAGCTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8750.88 Da        Isoelectric Point: 4.4217

>AT35318 WP_178885951.1 NZ_AP022321:2089222-2089452 [Veillonella nakazawae]
MTTAKLFENGRSQAVRLPKEFRFNGDEVIINKIGNVVLLMPKDDEWAGFVAGLSLFTDDFMYNGREDIDHQERETL

Download         Length: 231 bp

>AT35318 NZ_AP022321:2089222-2089452 [Veillonella nakazawae]
ATGACCACAGCAAAGCTATTCGAAAATGGCCGCAGCCAGGCTGTACGATTACCAAAAGAATTTCGGTTTAATGGTGATGA
AGTAATCATCAACAAAATAGGAAATGTAGTTTTACTTATGCCAAAAGACGATGAGTGGGCAGGATTTGTAGCCGGTTTAT
CATTATTTACAGATGATTTTATGTATAACGGACGGGAAGATATTGATCATCAGGAGCGTGAAACCTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References