Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 440130..440607 Replicon chromosome
Accession NZ_AP022321
Organism Veillonella nakazawae strain T1-7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VEIT17_RS01895 Protein ID WP_178884498.1
Coordinates 440341..440607 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C4FSP1
Locus tag VEIT17_RS01890 Protein ID WP_005387906.1
Coordinates 440130..440351 (+) Length 74 a.a.

Genomic Context

VEIT17_RS01875VEIT17_RS01880VEIT17_RS01890VEIT17_RS01895VEIT17_RS01900VEIT17_RS01905VEIT17_RS01915VEIT17_RS01920VEIT17_RS01885VEIT17_RS01910
Location: 436074..437522 (1449 bp)
Type: Others
Protein ID: WP_178884495.1
Location: 437653..438174 (522 bp)
Type: Others
Protein ID: WP_178884496.1
Location: 440130..440351 (222 bp)
Type: Antitoxin
Protein ID: WP_005387906.1
Location: 440341..440607 (267 bp)
Type: Toxin
Protein ID: WP_178884498.1
Location: 440618..440830 (213 bp)
Type: Others
Protein ID: WP_178884500.1
Location: 440897..441982 (1086 bp)
Type: Others
Protein ID: WP_178884501.1
Location: 443135..443938 (804 bp)
Type: Others
Protein ID: WP_178884505.1
Location: 443950..444888 (939 bp)
Type: Others
Protein ID: WP_039969603.1
Location: 438228..439601 (1374 bp)
Type: Others
Protein ID: WP_060924140.1
Location: 442077..442868 (792 bp)
Type: Others
Protein ID: WP_178884503.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VEIT17_RS01875436074..437522+1449WP_178884495.1hypothetical protein-
VEIT17_RS01880437653..438174+522WP_178884496.1DUF4178 domain-containing protein-
VEIT17_RS01885438228..439601-1374WP_060924140.1MFS transporter-
VEIT17_RS01890440130..440351+222WP_005387906.1hypothetical proteinAntitoxin
VEIT17_RS01895440341..440607+267WP_178884498.1type II toxin-antitoxin system RelE/ParE family toxinToxin
VEIT17_RS01900440618..440830+213WP_178884500.1hypothetical protein-
VEIT17_RS01905440897..441982+1086WP_178884501.1hypothetical protein-
VEIT17_RS01910442077..442868-792WP_178884503.1carbon-nitrogen family hydrolase-
VEIT17_RS01915443135..443938+804WP_178884505.1polysaccharide deacetylase family protein-
VEIT17_RS01920443950..444888+939WP_039969603.1phosphodiester glycosidase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10522.14 Da        Isoelectric Point: 10.2849

>T35317 WP_178884498.1 NZ_AP022321:440341-440607 [Veillonella nakazawae]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVENPRYSGKSLIGSKTGLWRYRIGNYRVIADINDDRCIILALEV
GHRKDIYK

Download         Length: 267 bp

>T35317 NZ_AP022321:440341-440607 [Veillonella nakazawae]
ATGGCTTATAAACTTGAGTTCTCTAAACGATTTGACAAGCAATTTTCTAAACTCGATAAATCAACACAACGTTATCTCTT
TAATTGGCTTATCAAGAACGTAGATAATGTAGAAAATCCTAGATATTCAGGAAAATCACTAATAGGTAGTAAGACAGGGC
TGTGGCGTTATCGCATTGGTAATTATAGAGTCATTGCTGATATTAATGATGATAGATGTATTATTTTAGCCTTAGAAGTG
GGGCACAGAAAAGATATTTACAAATAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8499.71 Da        Isoelectric Point: 4.3700

>AT35317 WP_005387906.1 NZ_AP022321:440130-440351 [Veillonella nakazawae]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYKQDPVTYSVAEMRAKYGL

Download         Length: 222 bp

>AT35317 NZ_AP022321:440130-440351 [Veillonella nakazawae]
ATGGCAAATATTTCAGTCCGTTTAAATGAACAAGAAGAAGAGTTATTTAAAACATATGCCGAGTTTATGGATGAAACACT
TTCTACTCTCTTTAAGAAGGCTTTACTAGAAAAGATTGAAGATGAATTTGATCTTAAGGTAGGTCAAAAAGCATTAGCAG
AATATAAGCAAGATCCTGTTACTTATTCTGTGGCGGAAATGCGTGCAAAATATGGCTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7YQA8

References