Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019029..2019195 Replicon chromosome
Accession NZ_AP022268
Organism Raoultella ornithinolytica strain WP8-W19-CRE-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019087..2019190 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019029..2019195 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R88_RS09395 2014167..2016227 + 2061 WP_044350916.1 oligopeptidase B -
H7R88_RS09400 2016233..2016892 - 660 WP_004863981.1 exodeoxyribonuclease X -
H7R88_RS09405 2016971..2017201 - 231 WP_004863978.1 DNA polymerase III subunit theta -
H7R88_RS09410 2017328..2017702 + 375 WP_004863975.1 CopC domain-containing protein YobA -
H7R88_RS09415 2017706..2018575 + 870 WP_004863974.1 copper homeostasis membrane protein CopD -
H7R88_RS09420 2018592..2018930 + 339 WP_015584012.1 YebY family protein -
- 2019029..2019195 - 167 - - Antitoxin
- 2019087..2019190 + 104 - - Toxin
H7R88_RS09425 2019500..2019643 - 144 WP_054828791.1 Ecr family regulatory small membrane protein -
H7R88_RS09430 2019764..2020735 - 972 WP_172412537.1 VirK/YbjX family protein -
H7R88_RS09435 2020878..2021522 + 645 WP_004863967.1 protein-serine/threonine phosphatase -
H7R88_RS09440 2021528..2021719 - 192 WP_004863962.1 YebW family protein -
H7R88_RS09445 2021813..2022052 - 240 WP_004863958.1 YebV family protein -
H7R88_RS09450 2022167..2023600 - 1434 WP_072046549.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T35147 NZ_AP022268:2019087-2019190 [Raoultella ornithinolytica]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 167 bp

>AT35147 NZ_AP022268:c2019195-2019029 [Raoultella ornithinolytica]
CAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGCGTCAGGTTTTCCAGTCCGCAACAAAAGTGGT
CGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References