35060

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2595219..2596933 Replicon chromosome
Accession NZ_AP022241
Organism Aeromonas caviae strain WP8-S18-CRE-01

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag H7R78_RS12155 Protein ID WP_125117290.1
Coordinates 2596280..2596933 (-) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag H7R78_RS12150 Protein ID WP_125117289.1
Coordinates 2595219..2596283 (-) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R78_RS12140 2591300..2592013 - 714 WP_125117287.1 M48 family metallopeptidase -
H7R78_RS12145 2592013..2595144 - 3132 WP_125117288.1 HsdR family type I site-specific deoxyribonuclease -
H7R78_RS12150 2595219..2596283 - 1065 WP_125117289.1 macro domain-containing protein Antitoxin
H7R78_RS12155 2596280..2596933 - 654 WP_125117290.1 DUF4433 domain-containing protein Toxin
H7R78_RS12160 2597211..2598569 - 1359 WP_125117291.1 restriction endonuclease subunit S -
H7R78_RS12165 2598566..2599057 - 492 WP_125117292.1 DUF1016 family protein -
H7R78_RS12170 2599054..2601504 - 2451 WP_125117293.1 type I restriction-modification system subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2571784..2636759 64975


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25444.06 Da        Isoelectric Point: 7.0176

>T35060 WP_125117290.1 NZ_AP022241:c2596933-2596280 [Aeromonas caviae]
MAYDYSQSLNPQKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPRRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLERIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T35060 NZ_AP022241:c2596933-2596280 [Aeromonas caviae]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGCAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCACGCCATCCGGTGCCGCTGGCGCCTTACGGCGTGTTGAATGACTATGTACCCTTCTACTTCACGCCG
TTTTCGCCCATGCTCAGCAATATTCACTCGGGCCGCGGTGTTCCCCGGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAATTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGTCGATCTTGGCGATCTGGAGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGACGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCATTGCTGGGTGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAATGCATGAATCGGGTGGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39657.81 Da        Isoelectric Point: 6.8633

>AT35060 WP_125117289.1 NZ_AP022241:c2596283-2595219 [Aeromonas caviae]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSRQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT35060 NZ_AP022241:c2596283-2595219 [Aeromonas caviae]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTGGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGAAAGGGGATTGCCTTGATGTTCAAAGAGCGGTTCCCGGCCAATATGCGTGCCTATGCCGAGGCGTGCAAGCAGGGTG
ACGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTAGGGCCGCGCTGGATCGTCAACTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGACGGTTTGCAGGATCTGCGGGCCTGGTTACAAGCGCAGCA
GGTCTCTTCGATTGCCATTCCACCACTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCGGAGGTCAAACAGGCGATCGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTCGACAATACCAAAATGTGGCCAAGCGCGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCCTGATTGCTGAACTGGTGCGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAGATCCAGAAGCTGGCCTGGTTTCTGGCTCGGGTCATTGGCCGAAACCCGCTGGGGGATCCGTTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACTCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATTCCGGATAGCAAGCCGTTTGATGTTATCTGGTTTAATGAGGCTAAAAAACAAGAGCTTGCCGTTTATCT
CCAGACCGAGGCCAAAGCATTTTTACCAATACTGGAGCAGACGACCGCGTTAATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTTGATTGGTTGATCGCCGAAGAGGGCTGTGCGCCGACGCTGAGCGCGTTGCGTGAGGGGTTG
CATCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCGCGGCTGTTTGATGATCGCAGCCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGGTTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References