Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2167881..2168152 Replicon chromosome
Accession NZ_AP022222
Organism Escherichia coli strain WP8-S17-ESBL-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2168011..2168114 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2167881..2168152 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R20_RS10210 2164436..2165098 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R20_RS10215 2165122..2165778 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
H7R20_RS10220 2165880..2166110 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R20_RS10225 2166249..2166623 + 375 WP_000204705.1 CopC domain-containing protein YobA -
H7R20_RS10230 2166627..2167499 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
H7R20_RS10235 2167512..2167853 + 342 WP_000976481.1 YebY family protein -
- 2167881..2168152 - 272 - - Antitoxin
- 2168011..2168114 + 104 - - Toxin
H7R20_RS10240 2168249..2168905 + 657 WP_001546849.1 protein-serine/threonine phosphatase -
H7R20_RS10245 2168906..2169097 - 192 WP_001296140.1 YebW family protein -
H7R20_RS10250 2169202..2169438 - 237 WP_001295499.1 DUF1480 family protein -
H7R20_RS10255 2169556..2170995 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2144094..2184702 40608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T35021 NZ_AP022222:2168011-2168114 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT35021 NZ_AP022222:c2168152-2167881 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References