Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2213568..2213839 | Replicon | chromosome |
| Accession | NZ_AP022221 | ||
| Organism | Escherichia coli strain WP8-S17-ESBL-08 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2213698..2213801 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2213568..2213839 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7K50_RS10525 | 2210123..2210785 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| H7K50_RS10530 | 2210809..2211465 | - | 657 | WP_000011653.1 | carbon-nitrogen hydrolase family protein | - |
| H7K50_RS10535 | 2211567..2211797 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| H7K50_RS10540 | 2211936..2212310 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| H7K50_RS10545 | 2212314..2213186 | + | 873 | WP_001551232.1 | copper homeostasis membrane protein CopD | - |
| H7K50_RS10550 | 2213199..2213540 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2213568..2213839 | - | 272 | - | - | Antitoxin |
| - | 2213698..2213801 | + | 104 | - | - | Toxin |
| H7K50_RS10555 | 2213936..2214592 | + | 657 | WP_001551231.1 | protein-serine/threonine phosphatase | - |
| H7K50_RS10560 | 2214593..2214784 | - | 192 | WP_001296140.1 | YebW family protein | - |
| H7K50_RS10565 | 2214889..2215125 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| H7K50_RS10570 | 2215243..2216682 | - | 1440 | WP_024186439.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2173252..2229679 | 56427 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T34993 NZ_AP022221:2213698-2213801 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT34993 NZ_AP022221:c2213839-2213568 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
