Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1972593..1972864 Replicon chromosome
Accession NZ_AP022215
Organism Escherichia coli strain WP8-S17-ESBL-05

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1972723..1972826 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1972593..1972864 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R13_RS09310 1969148..1969810 - 663 WP_182913684.1 exodeoxyribonuclease X -
H7R13_RS09315 1969834..1970490 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H7R13_RS09320 1970592..1970822 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R13_RS09325 1970961..1971335 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H7R13_RS09330 1971339..1972211 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H7R13_RS09335 1972224..1972565 + 342 WP_000976472.1 YebY family protein -
- 1972593..1972864 - 272 - - Antitoxin
- 1972723..1972826 + 104 - - Toxin
H7R13_RS09340 1972961..1973617 + 657 WP_000812710.1 protein-serine/threonine phosphatase -
H7R13_RS09345 1973618..1973809 - 192 WP_001296140.1 YebW family protein -
H7R13_RS09350 1973914..1974150 - 237 WP_001295499.1 DUF1480 family protein -
H7R13_RS09355 1974268..1975707 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34960 NZ_AP022215:1972723-1972826 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34960 NZ_AP022215:c1972864-1972593 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References