Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 4626709..4627848 | Replicon | chromosome |
| Accession | NZ_AP022213 | ||
| Organism | Pseudomonas otitidis strain WP8-S17-CRE-03 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | H7K70_RS21405 | Protein ID | WP_182852964.1 |
| Coordinates | 4626709..4627458 (-) | Length | 250 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A1E4WFB3 |
| Locus tag | H7K70_RS21410 | Protein ID | WP_044405544.1 |
| Coordinates | 4627477..4627848 (-) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7K70_RS21395 | 4624380..4625741 | - | 1362 | WP_160482899.1 | DNA recombination protein RmuC | - |
| H7K70_RS21400 | 4625908..4626321 | - | 414 | WP_044405541.1 | sel1 repeat family protein | - |
| H7K70_RS21405 | 4626709..4627458 | - | 750 | WP_182852964.1 | RES family NAD+ phosphorylase | Toxin |
| H7K70_RS21410 | 4627477..4627848 | - | 372 | WP_044405544.1 | XRE family transcriptional regulator | Antitoxin |
| H7K70_RS21415 | 4627981..4628463 | + | 483 | WP_182850756.1 | GreA/GreB family elongation factor | - |
| H7K70_RS21420 | 4628500..4628895 | + | 396 | WP_044405547.1 | hypothetical protein | - |
| H7K70_RS21425 | 4629121..4629273 | + | 153 | WP_182852994.1 | hypothetical protein | - |
| H7K70_RS21430 | 4629301..4629726 | - | 426 | WP_074971868.1 | hypothetical protein | - |
| H7K70_RS21435 | 4629836..4631440 | - | 1605 | WP_074971869.1 | M28 family peptidase | - |
| H7K70_RS21440 | 4631716..4632381 | - | 666 | WP_044405551.1 | class I SAM-dependent methyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 250 a.a. Molecular weight: 28191.07 Da Isoelectric Point: 6.9626
>T34949 WP_182852964.1 NZ_AP022213:c4627458-4626709 [Pseudomonas otitidis]
MDIWSACDGERHITPLRGRVVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAAARLETAMAEGAFYRFVLWSGMATPPPSGRILSEHASFEARFQVERGVSLQNPPFDAYPALLDRRDY
RATQALGAAMRTAGVEAFEYRSARCPQQGLNIALFTPDAFTERRPRNLTPWFCETTADYVAYKHAQAPDQPRLFRREAFL
VDGVIPQPA
MDIWSACDGERHITPLRGRVVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAAARLETAMAEGAFYRFVLWSGMATPPPSGRILSEHASFEARFQVERGVSLQNPPFDAYPALLDRRDY
RATQALGAAMRTAGVEAFEYRSARCPQQGLNIALFTPDAFTERRPRNLTPWFCETTADYVAYKHAQAPDQPRLFRREAFL
VDGVIPQPA
Download Length: 750 bp
>T34949 NZ_AP022213:c4627458-4626709 [Pseudomonas otitidis]
ATGGACATCTGGAGCGCATGCGACGGCGAACGCCACATCACCCCCCTGCGCGGGCGCGTGGTGCGCCTGGTGGAGAGCCA
GGAACAGGTGGCGACCCTGCAACTGGTGGACAACCTCGCCGAACAGGCCCTGCTGGAGGAACTCATCGAGACCAGCAAAC
CGCCCCTGCCGCGCAGCGCCGAGCCGCTGCACTACCTGCTCAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGCTCG
CGCTTCGGCACGGTGCACGAGCCCAGCCTGTTCTACGCCGCCGCGCGCCTGGAGACGGCCATGGCCGAAGGCGCCTTCTA
CCGCTTCGTGCTGTGGAGCGGCATGGCCACCCCACCGCCCAGCGGACGCATCCTCTCGGAGCACGCCTCCTTCGAGGCGC
GCTTCCAGGTGGAGCGCGGCGTGAGCCTGCAGAACCCGCCGTTCGATGCCTACCCGGCGCTGCTCGATCGCCGCGACTAC
CGTGCCACCCAGGCCCTGGGGGCGGCCATGCGTACCGCCGGGGTCGAAGCCTTCGAATACCGCTCCGCCCGCTGCCCGCA
GCAGGGGCTGAACATCGCCCTGTTCACCCCCGACGCCTTCACCGAACGGCGCCCGCGCAACCTCACCCCCTGGTTCTGCG
AAACCACGGCCGACTACGTCGCCTACAAGCACGCCCAGGCGCCGGACCAGCCTCGTCTGTTCCGCCGCGAAGCCTTCCTG
GTGGACGGCGTCATCCCCCAGCCGGCGTGA
ATGGACATCTGGAGCGCATGCGACGGCGAACGCCACATCACCCCCCTGCGCGGGCGCGTGGTGCGCCTGGTGGAGAGCCA
GGAACAGGTGGCGACCCTGCAACTGGTGGACAACCTCGCCGAACAGGCCCTGCTGGAGGAACTCATCGAGACCAGCAAAC
CGCCCCTGCCGCGCAGCGCCGAGCCGCTGCACTACCTGCTCAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGCTCG
CGCTTCGGCACGGTGCACGAGCCCAGCCTGTTCTACGCCGCCGCGCGCCTGGAGACGGCCATGGCCGAAGGCGCCTTCTA
CCGCTTCGTGCTGTGGAGCGGCATGGCCACCCCACCGCCCAGCGGACGCATCCTCTCGGAGCACGCCTCCTTCGAGGCGC
GCTTCCAGGTGGAGCGCGGCGTGAGCCTGCAGAACCCGCCGTTCGATGCCTACCCGGCGCTGCTCGATCGCCGCGACTAC
CGTGCCACCCAGGCCCTGGGGGCGGCCATGCGTACCGCCGGGGTCGAAGCCTTCGAATACCGCTCCGCCCGCTGCCCGCA
GCAGGGGCTGAACATCGCCCTGTTCACCCCCGACGCCTTCACCGAACGGCGCCCGCGCAACCTCACCCCCTGGTTCTGCG
AAACCACGGCCGACTACGTCGCCTACAAGCACGCCCAGGCGCCGGACCAGCCTCGTCTGTTCCGCCGCGAAGCCTTCCTG
GTGGACGGCGTCATCCCCCAGCCGGCGTGA
Antitoxin
Download Length: 124 a.a. Molecular weight: 13690.98 Da Isoelectric Point: 10.6556
>AT34949 WP_044405544.1 NZ_AP022213:c4627848-4627477 [Pseudomonas otitidis]
MSALTRPHLDPDAVLAKALLNTREQLGLTRQQLADIVGVHRTVVTRWADAGSIRPQSKTGELALLVIRIYRALFALFGGN
LEDMRHFLRTENRHLGGVPLELMGQVQGLVRVVEYLDAIRGKV
MSALTRPHLDPDAVLAKALLNTREQLGLTRQQLADIVGVHRTVVTRWADAGSIRPQSKTGELALLVIRIYRALFALFGGN
LEDMRHFLRTENRHLGGVPLELMGQVQGLVRVVEYLDAIRGKV
Download Length: 372 bp
>AT34949 NZ_AP022213:c4627848-4627477 [Pseudomonas otitidis]
ATGAGCGCGCTGACCCGCCCCCACCTTGATCCCGACGCCGTCCTGGCCAAGGCCCTGCTCAACACCCGCGAGCAACTGGG
GCTGACCCGCCAGCAACTGGCCGACATCGTCGGCGTCCACCGCACCGTCGTCACCCGCTGGGCCGACGCCGGCAGCATCC
GCCCGCAGAGCAAGACCGGTGAACTGGCGCTGCTGGTGATCCGCATCTACCGCGCGCTGTTCGCGTTGTTCGGCGGCAAC
CTCGAGGACATGCGCCACTTCCTGCGCACCGAGAACCGTCACCTTGGCGGCGTGCCCCTGGAGCTGATGGGGCAGGTGCA
GGGGCTGGTGCGGGTGGTGGAGTACCTCGACGCCATTCGCGGCAAGGTCTGA
ATGAGCGCGCTGACCCGCCCCCACCTTGATCCCGACGCCGTCCTGGCCAAGGCCCTGCTCAACACCCGCGAGCAACTGGG
GCTGACCCGCCAGCAACTGGCCGACATCGTCGGCGTCCACCGCACCGTCGTCACCCGCTGGGCCGACGCCGGCAGCATCC
GCCCGCAGAGCAAGACCGGTGAACTGGCGCTGCTGGTGATCCGCATCTACCGCGCGCTGTTCGCGTTGTTCGGCGGCAAC
CTCGAGGACATGCGCCACTTCCTGCGCACCGAGAACCGTCACCTTGGCGGCGTGCCCCTGGAGCTGATGGGGCAGGTGCA
GGGGCTGGTGCGGGTGGTGGAGTACCTCGACGCCATTCGCGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|