Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2257844..2258115 Replicon chromosome
Accession NZ_AP022207
Organism Escherichia coli strain WP7-S18-ESBL-09

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2257974..2258077 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2257844..2258115 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R37_RS10750 2254399..2255061 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R37_RS10755 2255085..2255741 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
H7R37_RS10760 2255843..2256073 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R37_RS10765 2256212..2256586 + 375 WP_000204705.1 CopC domain-containing protein YobA -
H7R37_RS10770 2256590..2257462 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
H7R37_RS10775 2257475..2257816 + 342 WP_001520705.1 YebY family protein -
- 2257844..2258115 - 272 - - Antitoxin
- 2257974..2258077 + 104 - - Toxin
H7R37_RS10780 2258212..2258868 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
H7R37_RS10785 2258869..2259060 - 192 WP_001296140.1 YebW family protein -
H7R37_RS10790 2259165..2259401 - 237 WP_001295499.1 DUF1480 family protein -
H7R37_RS10795 2259519..2260958 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34915 NZ_AP022207:2257974-2258077 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34915 NZ_AP022207:c2258115-2257844 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References