Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2271883..2272154 Replicon chromosome
Accession NZ_AP022173
Organism Escherichia coli strain WP7-S17-ESBL-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2272013..2272116 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2271883..2272154 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R26_RS10930 2268438..2269100 - 663 WP_016239019.1 exodeoxyribonuclease X -
H7R26_RS10935 2269124..2269780 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
H7R26_RS10940 2269882..2270112 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R26_RS10945 2270251..2270625 + 375 WP_000204705.1 CopC domain-containing protein YobA -
H7R26_RS10950 2270629..2271501 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
H7R26_RS10955 2271514..2271855 + 342 WP_000976481.1 YebY family protein -
- 2271883..2272154 - 272 - - Antitoxin
- 2272013..2272116 + 104 - - Toxin
H7R26_RS10960 2272251..2272907 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
H7R26_RS10965 2272908..2273099 - 192 WP_001296140.1 YebW family protein -
H7R26_RS10970 2273204..2273440 - 237 WP_001295499.1 DUF1480 family protein -
H7R26_RS10975 2273558..2274997 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2262710..2287993 25283


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34831 NZ_AP022173:2272013-2272116 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34831 NZ_AP022173:c2272154-2271883 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References