Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3014339..3014493 Replicon chromosome
Accession NZ_AP022126
Organism Enterobacter cloacae strain WP5-S18-CRE-02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3014355..3014458 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3014339..3014493 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R61_RS14585 3010615..3012057 + 1443 WP_032645266.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H7R61_RS14590 3012164..3012403 + 240 WP_008500472.1 YebV family protein -
H7R61_RS14595 3012438..3013082 - 645 WP_014884297.1 protein-serine/threonine phosphatase -
H7R61_RS14600 3013250..3014191 + 942 WP_014884298.1 VirK/YbjX family protein -
- 3014339..3014493 + 155 - - Antitoxin
- 3014355..3014458 - 104 - - Toxin
H7R61_RS14605 3014597..3014935 - 339 WP_014884299.1 YebY family protein -
H7R61_RS14610 3014952..3015821 - 870 WP_014884300.1 copper homeostasis membrane protein CopD -
H7R61_RS14615 3015823..3016194 - 372 WP_014884301.1 CopC domain-containing protein YobA -
H7R61_RS14620 3016332..3016562 + 231 WP_013096102.1 DNA polymerase III subunit theta -
H7R61_RS14625 3016673..3017323 + 651 WP_014884302.1 carbon-nitrogen hydrolase family protein -
H7R61_RS14630 3017348..3018010 + 663 WP_014884303.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34660 NZ_AP022126:c3014458-3014355 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 155 bp

>AT34660 NZ_AP022126:3014339-3014493 [Enterobacter cloacae]
TGTCTTTCATACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTG
CGCTAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References