Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2281577..2281724 Replicon chromosome
Accession NZ_AP022112
Organism Klebsiella quasipneumoniae strain WP5-W18-ESBL-06

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2281581..2281683 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2281577..2281724 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R83_RS11205 2277093..2278526 + 1434 WP_053810194.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H7R83_RS11210 2278643..2278882 + 240 WP_182937354.1 YebV family protein -
H7R83_RS11215 2278980..2279171 + 192 WP_002911395.1 YebW family protein -
H7R83_RS11220 2279168..2279821 - 654 WP_062914107.1 protein-serine/threonine phosphatase -
H7R83_RS11225 2279978..2280946 + 969 WP_004203383.1 VirK/YbjX family protein -
H7R83_RS11230 2281050..2281193 + 144 WP_032425946.1 Ecr family regulatory small membrane protein -
- 2281577..2281724 + 148 - - Antitoxin
- 2281581..2281683 - 103 - - Toxin
H7R83_RS11235 2281842..2282180 - 339 WP_002911404.1 YebY family protein -
H7R83_RS11240 2282197..2283066 - 870 WP_064183814.1 copper homeostasis membrane protein CopD -
H7R83_RS11245 2283070..2283444 - 375 WP_135698781.1 CopC domain-containing protein YobA -
H7R83_RS11250 2283557..2283787 + 231 WP_002911406.1 DNA polymerase III subunit theta -
H7R83_RS11255 2283866..2284525 + 660 WP_004203387.1 exodeoxyribonuclease X -
H7R83_RS11260 2284529..2286589 - 2061 WP_032456310.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T34600 NZ_AP022112:c2281683-2281581 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT34600 NZ_AP022112:2281577-2281724 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References