34523

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021887..2022158 Replicon chromosome
Accession NZ_AP022105
Organism Escherichia coli strain WP5-S17-ESBL-10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2022017..2022120 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021887..2022158 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R00_RS09540 2018442..2019104 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R00_RS09545 2019128..2019784 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H7R00_RS09550 2019886..2020116 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R00_RS09555 2020255..2020629 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R00_RS09560 2020633..2021505 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H7R00_RS09565 2021518..2021859 + 342 WP_000976476.1 YebY family protein -
- 2021887..2022158 - 272 - - Antitoxin
- 2022017..2022120 + 104 - - Toxin
H7R00_RS09570 2022255..2022911 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H7R00_RS09575 2022912..2023103 - 192 WP_000457842.1 YebW family protein -
H7R00_RS09580 2023208..2023444 - 237 WP_001295499.1 DUF1480 family protein -
H7R00_RS09585 2023562..2025001 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34523 NZ_AP022105:2022017-2022120 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34523 NZ_AP022105:c2022158-2021887 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References