Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202302..2202573 Replicon chromosome
Accession NZ_AP022098
Organism Escherichia coli strain WP4-S18-ESBL-09

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202432..2202535 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202302..2202573 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R19_RS10225 2198857..2199519 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R19_RS10230 2199543..2200199 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
H7R19_RS10235 2200301..2200531 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R19_RS10240 2200670..2201044 + 375 WP_022645803.1 CopC domain-containing protein YobA -
H7R19_RS10245 2201048..2201920 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
H7R19_RS10250 2201933..2202274 + 342 WP_000976472.1 YebY family protein -
- 2202302..2202573 - 272 - - Antitoxin
- 2202432..2202535 + 104 - - Toxin
H7R19_RS10255 2202670..2203326 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
H7R19_RS10260 2203327..2203518 - 192 WP_001296140.1 YebW family protein -
H7R19_RS10265 2203623..2203859 - 237 WP_001295499.1 DUF1480 family protein -
H7R19_RS10270 2203977..2205416 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34497 NZ_AP022098:2202432-2202535 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34497 NZ_AP022098:c2202573-2202302 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References