Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2135044..2135315 Replicon chromosome
Accession NZ_AP022095
Organism Escherichia coli strain WP4-S18-ESBL-08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2135174..2135277 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2135044..2135315 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R08_RS10200 2131600..2132262 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R08_RS10205 2132286..2132942 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
H7R08_RS10210 2133044..2133274 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R08_RS10215 2133413..2133787 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R08_RS10220 2133791..2134663 + 873 WP_108429901.1 copper homeostasis membrane protein CopD -
H7R08_RS10225 2134676..2135017 + 342 WP_000976472.1 YebY family protein -
- 2135044..2135315 - 272 - - Antitoxin
- 2135174..2135277 + 104 - - Toxin
H7R08_RS10230 2135412..2136068 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H7R08_RS10235 2136069..2136260 - 192 WP_001296140.1 YebW family protein -
H7R08_RS10240 2136365..2136601 - 237 WP_001295499.1 DUF1480 family protein -
H7R08_RS10245 2136719..2138158 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34462 NZ_AP022095:2135174-2135277 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34462 NZ_AP022095:c2135315-2135044 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References