Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2174912..2175183 Replicon chromosome
Accession NZ_AP022069
Organism Escherichia coli strain WP4-W18-ESBL-09

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2175042..2175145 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2174912..2175183 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R28_RS10155 2171467..2172129 - 663 WP_000944256.1 exodeoxyribonuclease X -
H7R28_RS10160 2172153..2172809 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
H7R28_RS10165 2172911..2173141 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R28_RS10170 2173280..2173654 + 375 WP_000204705.1 CopC domain-containing protein YobA -
H7R28_RS10175 2173658..2174530 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
H7R28_RS10180 2174543..2174884 + 342 WP_001520705.1 YebY family protein -
- 2174912..2175183 - 272 - - Antitoxin
- 2175042..2175145 + 104 - - Toxin
H7R28_RS10185 2175280..2175936 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
H7R28_RS10190 2175937..2176128 - 192 WP_001296140.1 YebW family protein -
H7R28_RS10195 2176233..2176469 - 237 WP_001295499.1 DUF1480 family protein -
H7R28_RS10200 2176587..2178026 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T34359 NZ_AP022069:2175042-2175145 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT34359 NZ_AP022069:c2175183-2174912 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References