Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2671446..2671714 Replicon chromosome
Accession NZ_AP022064
Organism Escherichia coli strain WP4-W18-ESBL-08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2671484..2671586 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2671446..2671714 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R03_RS13135 2668604..2670043 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H7R03_RS13140 2670160..2670396 + 237 WP_001295499.1 DUF1480 family protein -
H7R03_RS13145 2670501..2670692 + 192 WP_001296140.1 YebW family protein -
H7R03_RS13150 2670693..2671349 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 2671446..2671714 + 269 - - Antitoxin
- 2671484..2671586 - 103 - - Toxin
H7R03_RS13155 2671744..2672085 - 342 WP_000976472.1 YebY family protein -
H7R03_RS13160 2672098..2672970 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
H7R03_RS13165 2672974..2673348 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H7R03_RS13170 2673487..2673717 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H7R03_RS13175 2673819..2674475 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H7R03_RS13180 2674499..2675161 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2654831..2677218 22387


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T34320 NZ_AP022064:c2671586-2671484 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT34320 NZ_AP022064:2671446-2671714 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References