Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3244338..3244854 Replicon chromosome
Accession NZ_AP022055
Organism Pseudomonas putida strain WP4-W18-CRE-03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H7R82_RS14865 Protein ID WP_125861722.1
Coordinates 3244338..3244619 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H7R82_RS14870 Protein ID WP_132444928.1
Coordinates 3244609..3244854 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7R82_RS14835 3239501..3239719 - 219 WP_071557701.1 AlpA family transcriptional regulator -
H7R82_RS14840 3240525..3241493 + 969 WP_135325411.1 DUF932 domain-containing protein -
H7R82_RS14845 3241568..3242572 + 1005 WP_182941133.1 YqaJ viral recombinase family protein -
H7R82_RS14850 3242665..3243615 + 951 WP_182941136.1 hydrolase or metal-binding protein -
H7R82_RS14855 3243587..3244084 + 498 WP_034019467.1 DNA repair protein RadC -
H7R82_RS14860 3244095..3244268 + 174 WP_165362587.1 hypothetical protein -
H7R82_RS14865 3244338..3244619 - 282 WP_125861722.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H7R82_RS14870 3244609..3244854 - 246 WP_132444928.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H7R82_RS14875 3245024..3246550 + 1527 WP_167827541.1 transposase -
H7R82_RS14880 3246658..3247020 - 363 WP_135325415.1 cupin domain-containing protein -
H7R82_RS14885 3247035..3248432 - 1398 WP_135325416.1 FAD-binding oxidoreductase -
H7R82_RS14890 3248591..3249418 + 828 WP_135325417.1 nuclear transport factor 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10781.67 Da        Isoelectric Point: 10.7574

>T34286 WP_125861722.1 NZ_AP022055:c3244619-3244338 [Pseudomonas putida]
MTYKLEFLPSALKEWEKLGHTVREQAKKKLRERLEAPKVQADALRDLPGHYKIKLRTAGYRLVYRVEDDRVVVMVVAVGK
RERSAAYKAAGKR

Download         Length: 282 bp

>T34286 NZ_AP022055:c3244619-3244338 [Pseudomonas putida]
ATGACCTATAAGCTCGAGTTCCTGCCCTCGGCGCTGAAGGAATGGGAGAAGCTGGGTCATACGGTGCGTGAGCAGGCAAA
GAAAAAACTGCGTGAGCGGCTGGAAGCACCAAAGGTTCAGGCTGATGCCCTCAGGGATCTGCCTGGGCACTACAAGATCA
AGCTCCGAACAGCAGGCTATCGATTGGTCTATCGGGTCGAAGATGATCGTGTGGTTGTGATGGTGGTCGCAGTGGGCAAG
CGTGAACGAAGTGCAGCTTACAAGGCAGCAGGTAAGCGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8668.00 Da        Isoelectric Point: 4.1630

>AT34286 WP_132444928.1 NZ_AP022055:c3244854-3244609 [Pseudomonas putida]
MQSVLADVAVSVSELKKNPTGVMAGAGGMPVAVLNHNRVMGYMVPAELYEQMLERLDDLDLIDVVNARSGEKGVPVNLDD
L

Download         Length: 246 bp

>AT34286 NZ_AP022055:c3244854-3244609 [Pseudomonas putida]
ATGCAGAGTGTTTTGGCTGACGTTGCCGTGAGCGTTTCTGAGCTGAAGAAAAACCCCACCGGTGTCATGGCTGGTGCTGG
TGGCATGCCGGTCGCCGTTCTCAATCATAACCGCGTGATGGGGTACATGGTGCCAGCCGAGCTGTACGAGCAGATGCTGG
AGCGTCTGGACGATCTGGATCTGATCGATGTCGTTAATGCACGCTCTGGTGAGAAGGGTGTGCCGGTGAACCTGGATGAC
CTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References